Prasugrel-d5
- CAS NO.:1127252-92-9
- Empirical Formula: C20H20FNO3S
- Molecular Weight: 373.44
- MDL number: MFCD28899341
- Update Date: 2023-05-21 10:59:17
What is Prasugrel-d5?
Description
Prasugrel-d5 is intended for use as an internal standard for the quantification of prasugrel by GC- or LC-MS. Prasugrel is a prodrug form of the platelet purinergic P2Y12 receptor antagonist R-99224. Prasugrel (0.3 and 3 mg/kg) inhibits ex vivo washed platelet aggregation in rat platelet rich-plasma. In vivo, prasugrel prevents thrombus formation (ED50 = 0.68 mg/kg) and increases tail bleeding time in rats. Formulations containing prasugrel have been used in the prevention of blood clots.
The Uses of Prasugrel-d5
A novel labelled antiplatelet agent; it is a third-generation thienopyridine. Antiplatelet agent Prasugrel showed greater platelet inhibition and decreased incidence of ischemic events than Clopidogrel but may induce increased incidence of bleeding in patient with acute coronary syndrome
Properties of Prasugrel-d5
storage temp. | Store at -20°C |
solubility | Chloroform: slightly soluble,Methanol: slightly soluble |
form | A solid |
Safety information for Prasugrel-d5
Computed Descriptors for Prasugrel-d5
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