Posaconazole-d4
- CAS NO.:1133712-26-1
- Empirical Formula: C37H42F2N8O4
- Molecular Weight: 700.79
- MDL number: MFCD28899339
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-18 11:31:21
What is Posaconazole-d4?
Chemical properties
Off-White Foam
The Uses of Posaconazole-d4
Orally active labelled triazole antifungal.
What are the applications of Application
Posaconazole-d4 is a labelled triazole antifungal agent
What are the applications of Application
Posaconazole-d4, an isotope of posaconazole, was used as an internal standard and showed retention and ionization identical to those of posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
General Description
This stable-labeled internal standard is suitable for quantification of posaconazole levels in blood, serum, or plasma by HPLC or LC-MS/MS. The antifungal posaconazole is used to treat invasive and systemic fungal infections. As a result of significant drug interactions, therapeutic drug monitoring of posaconazole is recommended when administered with protease inhibitors (PIs) or non-nucleoside reverse transcriptase inhibitors (NNRTIs).
Liquid chromatography-mass spectrometry method for the quantification of posaconazole in human plasma: Application to pharmacokinetics following single-dose administration in the fasted state and with a high-fat meal
Properties of Posaconazole-d4
Melting point: | 170-172?C |
storage temp. | -20°C Freezer |
solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated), Methan |
form | Solid |
color | Off-White to Light Grey |
Stability: | Moisture Sensitive |
Safety information for Posaconazole-d4
Computed Descriptors for Posaconazole-d4
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