Posaconazole-d4
- CAS NO.:1133712-26-1
- Empirical Formula: C37H42F2N8O4
- Molecular Weight: 700.79
- MDL number: MFCD28899339
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is Posaconazole-d4?
Chemical properties
Off-White Foam
The Uses of Posaconazole-d4
Orally active labelled triazole antifungal.
What are the applications of Application
Posaconazole-d4 is a labelled triazole antifungal agent
What are the applications of Application
Posaconazole-d4, an isotope of posaconazole, was used as an internal standard and showed retention and ionization identical to those of posaconazole. Posaconazole is a broad-spectrum, second generation, triazole compound with antifungal activity.
General Description
This stable-labeled internal standard is suitable for quantification of posaconazole levels in blood, serum, or plasma by HPLC or LC-MS/MS. The antifungal posaconazole is used to treat invasive and systemic fungal infections. As a result of significant drug interactions, therapeutic drug monitoring of posaconazole is recommended when administered with protease inhibitors (PIs) or non-nucleoside reverse transcriptase inhibitors (NNRTIs).
Liquid chromatography-mass spectrometry method for the quantification of posaconazole in human plasma: Application to pharmacokinetics following single-dose administration in the fasted state and with a high-fat meal
Properties of Posaconazole-d4
Melting point: | 170-172?C |
storage temp. | -20°C Freezer |
solubility | Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly, Heated), Methan |
form | Solid |
color | Off-White to Light Grey |
Stability: | Moisture Sensitive |
Safety information for Posaconazole-d4
Computed Descriptors for Posaconazole-d4
New Products
Tert-butyl bis(2-chloroethyl)carbamate (S)-3-Aminobutanenitrile hydrochloride N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 4-Hydrazinobenzoic acid 3,4-Dibenzyloxybenzaldehyde 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) 4-HYDROXY BENZYL ALCOHOL 3-NITRO-2-METHYL ANILINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 4-methoxy-3,5-dinitropyridine 2-(Cyanocyclohexyl)acetic acid 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride tert-butyl 4- (ureidomethyl)benzylcarbamate diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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