Piperaquine
- CAS NO.：83764-65-2
- Empirical Formula: C29H32Cl2N6
- Molecular Weight: 535.51058
- SAFETY DATA SHEET (SDS)
What is Piperaquine?
Pharmaceutical Applications
A bisquinoline used to treat malaria in China since 1978. It
is structurally related to chloroquine, but active against chloroquine-
resistant P. falciparum. A combination with dihdyroartemisinin
has shown excellent tolerability and high cure
rates for multidrug-resistant falciparum malaria.
It is highly lipid-soluble and orally well absorbed. The elimination
half-life is 20–30 days and there is extensive metabolism.
Adverse effects are similar to chloroquine, but pruritus
is uncommon.
Safety information for Piperaquine
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