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HomeProduct name listPipecuronium bromide

Pipecuronium bromide

  • CAS NO.:52212-02-9
  • Empirical Formula: C35H62Br2N4O4
  • Molecular Weight: 762.69918
  • MDL number: MFCD00867696
  • EINECS: 257-740-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 20:33:22
Pipecuronium bromide Structural

What is Pipecuronium bromide?

The Uses of Pipecuronium bromide

Pipecuronium Bromide is a muscle relaxant and an anaesthesia used in patients undergoing coronary artery bypass graft surgery.

Definition

ChEBI: Pipecuronium bromide is a steroid ester.

brand name

Arduan (Organon).

General Description

Pipecurium bromide, 4,4 -(3 ,17 -dihydroxy-5 -androstan-2 ,16 -ylene)bis(1,1-dimeth-ylpiperazinium)dibromide diacetate (Arduan), is anondepolarizing muscle relaxant similar, both chemicallyand clinically, to pancuronium bromide. It is a long-actingdrug indicated as an adjunct to anesthesia and in patients undergoingmechanical ventilation.

Pharmacology

Pipecuronium bromide, an analogue of pancuronium, was developed in Hungary in 1980 and is marketed in Eastern Europe and the United S tates. The intubating dose is 0.07 mg kg–1. The onset time and time to recovery from block are similar to those of pancuronium, and excretion of the drug through the kidneys is significant (66%). In contrast to pancuronium, pipecuronium produces marked cardiovascular stability, having no vagolytic or sympathomimetic effects. It may therefore be useful during major surgery in patients with cardiac disease.

Properties of Pipecuronium bromide

Melting point: 262-264° (dec)
alpha  D25 +8.1° (c = 1 in water)
storage temp.  Store at -20°C
solubility  DMSO, Methanol (Slightly), Water (Slightly)
form  Solid
color  White to Off-White
CAS DataBase Reference 52212-02-9(CAS DataBase Reference)

Safety information for Pipecuronium bromide

Computed Descriptors for Pipecuronium bromide

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