Pipecuronium bromide
- CAS NO.:52212-02-9
- Empirical Formula: C35H62Br2N4O4
- Molecular Weight: 762.69918
- MDL number: MFCD00867696
- EINECS: 257-740-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is Pipecuronium bromide?
The Uses of Pipecuronium bromide
Pipecuronium Bromide is a muscle relaxant and an anaesthesia used in patients undergoing coronary artery bypass graft surgery.
Definition
ChEBI: Pipecuronium bromide is a steroid ester.
brand name
Arduan (Organon).
General Description
Pipecurium bromide, 4,4 -(3 ,17 -dihydroxy-5 -androstan-2 ,16 -ylene)bis(1,1-dimeth-ylpiperazinium)dibromide diacetate (Arduan), is anondepolarizing muscle relaxant similar, both chemicallyand clinically, to pancuronium bromide. It is a long-actingdrug indicated as an adjunct to anesthesia and in patients undergoingmechanical ventilation.
Pharmacology
Pipecuronium bromide, an analogue of pancuronium, was developed in Hungary in 1980 and is marketed in Eastern Europe and the United S tates. The intubating dose is 0.07 mg kg–1. The onset time and time to recovery from block are similar to those of pancuronium, and excretion of the drug through the kidneys is significant (66%). In contrast to pancuronium, pipecuronium produces marked cardiovascular stability, having no vagolytic or sympathomimetic effects. It may therefore be useful during major surgery in patients with cardiac disease.
Properties of Pipecuronium bromide
Melting point: | 262-264° (dec) |
alpha | D25 +8.1° (c = 1 in water) |
storage temp. | Store at -20°C |
solubility | DMSO, Methanol (Slightly), Water (Slightly) |
form | Solid |
color | White to Off-White |
CAS DataBase Reference | 52212-02-9(CAS DataBase Reference) |
Safety information for Pipecuronium bromide
Computed Descriptors for Pipecuronium bromide
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
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