PICROSIDE I
Synonym(s):;6′-Cinnamoylcatalpol
- CAS NO.：27409-30-9
- Empirical Formula: C24H28O11
- Molecular Weight: 492.47
- MDL number: MFCD29505480
- EINECS: 248-445-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-05 08:26:49
What is PICROSIDE I?
Description
Picroliv is a hepatoprotective mixture of compounds that is isolated from an herb native to the Himalayas. Picroside I is an iridoid glycoside found in picroliv. By itself, picroside I blocks changes in acid phosphatase activity, phospholipid levels, and lipid peroxide production induced by D-galactosamine in rat liver. Picroside I also enhances neurite outgrowth in PC12D cells induced by basic fibroblast growth factor and 7S nerve growth factor when given at 60 μM. At concentrations as low as 5 μM, picroside I enhances the ATPase activity of the efflux transporter P-glycoprotein.
The Uses of PICROSIDE I
Picroside I acts as an oxygen free radical scavenger and thus promotes anti-inflammatory activity and may be used in the treatment of arthritis.
Properties of PICROSIDE I
| Boiling point: | 778.6±60.0 °C(Predicted) |
| Density | 1.56±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | ethanol: soluble1mg/mL, clear, colorless |
| form | powder |
| pka | 12.70±0.70(Predicted) |
| color | White |
Safety information for PICROSIDE I
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for PICROSIDE I
| InChIKey | BSYHSWKTXMTFNF-NTLZGZQOSA-N |
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