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HomeProduct name listPhenidone

Phenidone

Synonym(s):Phenidone

  • CAS NO.:92-43-3
  • Empirical Formula: C9H10N2O
  • Molecular Weight: 162.19
  • MDL number: MFCD00003094
  • EINECS: 202-155-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-06 16:01:30
Phenidone Structural

What is Phenidone?

Chemical properties

light beige powder or crystals

The Uses of Phenidone

Phenidone is used as black and white photographic developer.

The Uses of Phenidone

Phenidone inhibits both the LO (lipoxygenase) and Cox (cyclooxygenase) pathways, the synthesis of Fos-related antigen protein, and is described as an anti-inflammatory and anti-oxidant compound. Phenidone has been shown to block neurotoxicity induced by kainate, and weakens oxidative stress induced by lipopolysaccharide.

What are the applications of Application

Phenidone is a dual LO (lipoxygenase) and Cox (cyclooxygenase) inhibitor

Flammability and Explosibility

Not classified

Safety Profile

Poison by ingestion and intraperitoneal routes. When heated to decomposition it emits toxic fumes of NOx.

Properties of Phenidone

Melting point: 119-121 °C(lit.)
Boiling point: 288.88°C (rough estimate)
Density  1.1436 (rough estimate)
vapor pressure  0.002Pa at 25℃
refractive index  1.5600 (estimate)
storage temp.  Sealed in dry,Room Temperature
solubility  methanol: 0.1 g/mL, clear
form  White to off-white solid.
pka 9.50±0.30(Predicted)
color  White to Light yellow to Light orange
Water Solubility  SOLUBLE IN HOT WATER
Merck  14,7309
BRN  131856
Stability: Stable, but light sensitive. Incompatible with strong acids, strong oxidizing agents, strong bases.
CAS DataBase Reference 92-43-3(CAS DataBase Reference)
NIST Chemistry Reference 1-Phenyl-3-pyrazolidinone(92-43-3)
EPA Substance Registry System 3-Pyrazolidinone, 1-phenyl- (92-43-3)

Safety information for Phenidone

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H302:Acute toxicity,oral
H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P273:Avoid release to the environment.
P391:Collect spillage. Hazardous to the aquatic environment
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P501:Dispose of contents/container to..…

Computed Descriptors for Phenidone

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