Palonosetron
- CAS NO.：149653-99-6
- Empirical Formula: C19H24N2O
- Molecular Weight: 296.41
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-03-13 11:54:02
What is Palonosetron?
Indications
Palonosetron is approved by the US FDA for acute and delayed CINV and PONV.
Biological Activity
Palonosetron is a highly selective, high-affinity 5-HT3 receptor antagonist. Due to its structural difference from the first-generation 5-HT3 receptor antagonists, palonosetron has an affinity for the 5-HT3 receptor at least 30 times that of other similar drugs.
in vitro
Palonosetron is neither an inhibitor of CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2D6, CYP2E1 and CYP3A4/5 (CYP2C19 not studied) nor does it induce the activity of CYP1A2, CYP2D6 or CYP3A4/5.
Properties of Palonosetron
| Boiling point: | 470.4±45.0 °C(Predicted) |
| Density | 1.24 |
| pka | 9.77±0.33(Predicted) |
Safety information for Palonosetron
Computed Descriptors for Palonosetron
New Products
4,4-Difluoropiperidine hydrochloride tert-butyl 9-methoxy-3-azaspiro[5.5]undecane-3-carboxylate Indole Methyl Resin N-Isopropylurea N,N-Dicyclohexylcarbodiimide(DCC) MELDRUMS ACID 5-METHYLISOXAZOLE-4-CARBOXYLIC ACID Magnessium Bis glycinate Zinc ascorbate 1-bromo-2-butyne 2-acetamidophenol 9(10H)-anthracenone Erythrosin B, 4-Piperidinopiperidine 2-((4-morpholinophenylamino) (methylthio) methylene) malononitrile 2,4-dihydroxybenzaldehyde 3-(4-morpholinophenylamino)-5-amino-1H-pyrazole-4-carbonitrile Methyl 2-methylquinoline-6-carboxylate 2,6-dichloro-4-nitropyridine 4-Bromo-2-chlorobenzonitrile 2-(benzylamino)acetic acid hydrochloride 4-(tert-Butoxycarbonylamino)but- 2-ynoic acid 3,4-dihydro-2H-benzo[b][1,4]dioxepine 1-Phenyl-1-cycloprppanecarboxylicacidRelated products of tetrahydrofuran
![1H-Benz[de]isoquinolin-1-one,2,4,5,6-tetrahydro-2-[(3S)-1-oxido-1-azabicyclo[2.2.2]oct-3-yl]-](https://img.chemicalbook.in/CAS/20180629/GIF/1021456-82-5.gif)
You may like
-
3-(4-amino-1-oxoisoindolin-2-yl)-1-methylpiperidine-2,6-dione 98%View Details -
1-methylindoline-2,3-dione 98%View Details
2058-74-4 -
614-19-7 98%View Details
614-19-7 -
3112-85-4 Methyl phenyl sulfone 98%View Details
3112-85-4 -
20677-73-0 (2,2-diethoxyethyl)methylamine 98%View Details
20677-73-0 -
3-(4-(hydroxyamino)-1-oxoisoindolin-2-yl)piperidine-2,6-dione 98%View Details
-
57381-49-4 2-bromo-4-chlorobenzonitrile 98%View Details
57381-49-4 -
4,6-dichloropyrimidine-5-carbaldehyde 98%View Details
5305-40-8
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.