Nomegestrol
- CAS NO.：58691-88-6
- Empirical Formula: C21H28O3
- Molecular Weight: 328.45
- MDL number: MFCD00867856
- EINECS: 200-258-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-25 23:13:37
What is Nomegestrol?
Description
Nomegestrol acetate is the 19-nor derivative of megestrol acetate, useful in the treatment of gynecological conditions associated with luteal deficiency.
Description
Nomegestrol is a derivative of 19-norprogesterone. It increases nuclear levels of the progesterone receptor in rat uterus when administered at a dose of 1 mg/animal.
Originator
Theramex (Monaco)
The Uses of Nomegestrol
A progestogen, derivatives of which are used in contraceptives and hormone therapies.
The Uses of Nomegestrol
Progetin used in implantable hormone replacement therapies.
Background
Nomegestrol is an ingredient in the EMA-authorised product Zoely.
What are the applications of Application
Nomegestrol is a progestogen, derivatives are used in contraceptives and hormone therapies
Definition
ChEBI: Nomegestrol is a corticosteroid hormone.
brand name
LUTENYL
General Description
Nomegestrol acetate, 17-hydroxy-6-methyl-19-norpregna-4,6-diene-3,20-dione acetate,is being investigated as the progestin component of anew oral contraceptive, in combination with the estrogenestradiol. This new combination, NOMAC/E2, is in phaseIII trials and would be the first oral contraceptive to utilizeestradiol itself as the estrogenic component. Structurally,NOMAC is considered a nor-progesterone derivative thatlacks the C19 methyl group in megestrol acetate.
Metabolism
Not Available
Properties of Nomegestrol
| Boiling point: | 502.6±50.0 °C(Predicted) |
| Density | 1.17±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform: soluble,DMSO: slightly soluble,Methanol: slightly soluble |
| pka | 12.99±0.60(Predicted) |
| form | A solid |
Safety information for Nomegestrol
Computed Descriptors for Nomegestrol
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium 3-Bromopyrazole (3aR,4R,5R,6aS)-hexahydro-5-Triethyl silyloxy-4-((E)-3-oxo-5-phenylpent-1- enyl)cyclopenta[b]furan-2-one. 1-Chlorocarbonyl-4-piperidinopiperidine 1-Bromo-4-phenyl-2-Butanone 4-Amino-2-fluoro-N-methylbenzamide 1,1'-Carbonyldiimidazole SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTIONRelated products of tetrahydrofuran
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