Nicotinoyl chloride hydrochloride

CAS NO.：20260-53-1
Empirical Formula: C6H5Cl2NO
Molecular Weight: 178.02
MDL number: MFCD00012820
EINECS: 243-648-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-11-03 20:31:17

What is Nicotinoyl chloride hydrochloride?

Chemical properties

white to off-white crystalline powder

The Uses of Nicotinoyl chloride hydrochloride

As a Nicotinic Acid analog, Nicotinoyl chloride hydrochloride can be used in the preparation of cardiovascular agents and renal drugs.

The Uses of Nicotinoyl chloride hydrochloride

Nicotinoyl chloride hydrochloride was used in the preparation of 1-[5-O-tert-butyldimethylsilyl-2-deoxy-2-fluoro-3-O-(3-pyridylcarbonyl)-β-D-ribofuranosyl]uracil, bis(ethylenedithio)tetrathiafulvalene derivatives and 7,16-dinicotinoylated or 7,16-diisonicotinoylated compounds via reaction with tetraaza[14]annulene and its complexes.

The Uses of Nicotinoyl chloride hydrochloride

Nicotinoyl chloride hydrochloride was used in the preparation of :

1-[5-O-tert-butyldimethylsilyl-2-deoxy-2-fluoro-3-O-(3-pyridylcarbonyl)-β-D-ribofuranosyl]uracil
7,16-dinicotinoylated and/or 7,16-diisonicotinoylated compounds via reaction with tetraaza[14]annulene and its complexes
bis(ethylenedithio)tetrathiafulvalene derivatives

Properties of Nicotinoyl chloride hydrochloride

Melting point:	151-157 °C(lit.)
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
form	Crystalline Powder
color	White to off-white
Water Solubility	It decomposes in water.
Sensitive	Moisture Sensitive
BRN	3655772
InChI	InChI=1S/C6H4ClNO.ClH/c7-6(9)5-2-1-3-8-4-5;/h1-4H;1H
CAS DataBase Reference	20260-53-1(CAS DataBase Reference)
EPA Substance Registry System	3-Pyridinecarbonyl chloride, hydrochloride (20260-53-1)

Safety information for Nicotinoyl chloride hydrochloride

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05
GHS Hazard Statements	H314:Skin corrosion/irritation
Precautionary Statement Codes	P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.