N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE

CAS NO.：1161205-27-1
Empirical Formula: C17H14N2O3
Molecular Weight: 294.3
MDL number: MFCD00947860
SAFETY DATA SHEET (SDS)
Update Date: 2022-12-21 16:56:50

What is N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE?

What are the applications of Application

PHCCC is a group I metabotropic glutamate receptor antagonist

Biological Activity

Group I metabotropic glutamate receptor antagonist (IC 50 ~ 3 μ M); 67 times more potent than (S)-4-carboxyphenylglycine ((S)-4-Carboxyphenylglycine). Also a positive allosteric modulator for mGlu 4a ; potentiates L-AP4-mediated inhibition of striatopallidal synaptic transmission in vitro . Displays antiParkinsonian effects in rats in vivo .

Properties of N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE

Boiling point:	579.1±50.0 °C(Predicted)
Density	1.41±0.1 g/cm3(Predicted)
storage temp.	Store at RT
pka	10.79±0.40(Predicted)

Safety information for N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE

Computed Descriptors for N-PHENYL-7-(HYDROXYIMINO)CYCLOPROPA[B]CHROMEN-1A-CARBOXAMIDE

New Products

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