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HomeProduct name listN-NITROSOPIPERIDINE

N-NITROSOPIPERIDINE

Synonym(s):Anti-47 kDa taipoxin-binding protein;Anti-Neuronal pentraxin I;Anti-NP1;Anti-NP-I

  • CAS NO.:100-75-4
  • Empirical Formula: C5H10N2O
  • Molecular Weight: 114.15
  • MDL number: MFCD00023652
  • EINECS: 202-886-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:52
N-NITROSOPIPERIDINE Structural

What is N-NITROSOPIPERIDINE?

Chemical properties

light yellow oily liquid

Chemical properties

N-Nitrosopiperidine is a clear, yellow, oily liquid.

The Uses of N-NITROSOPIPERIDINE

A carcinogenic nitrosocompound.

Definition

ChEBI: N-nitrosopiperidine is a nitrosamine that is piperidine in which the hydrogen attached to the nitrogen is replaced by a nitroso group. One of the many carcinogens detected in cigarette smoke, it is found in meat, cheese and spices that have been treated with the preservative sodium nitrite. It has a role as a carcinogenic agent, an apoptosis inducer, a mutagen and an environmental contaminant. It is a nitrosamine and a piperidine.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 36, p. 459, 1988 DOI: 10.1248/cpb.36.459

General Description

Light yellow oil or liquid. May be a carcinogen.

Air & Water Reactions

Water soluble.

Reactivity Profile

N-NITROSOPIPERIDINE may react with strong oxidizing agents, especially peroxyacids. .

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition N-NITROSOPIPERIDINE emits highly toxic fumes.

Fire Hazard

Flash point data are not available for N-NITROSOPIPERIDINE, but N-NITROSOPIPERIDINE is probably combustible.

Safety Profile

Confirmed carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by ingestion, intravenous, and subcutaneous routes. An experimental teratogen. Human mutation data reported. When heated to decomposition it emits toxic fumes of NOx. See also N-NITROSO COMPOUNDS.

Potential Exposure

N-Nitrosopiperidine is found in some foods and tobacco smoke. Used as a research chemical.

Carcinogenicity

N-Nitrosopiperidine is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals.

Shipping

UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3082 Environmentally hazardous substances, liquid, n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required

Incompatibilities

Nitrated organics range from slight to strong oxidizing agents. If mixed with reducing agents, including hydrides, sulfides and nitrides, they may begin a vigorous reaction. Reaction with aliphatic amines can release carcinogenic nitrosamines. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides. Light and UV may cause decomposition

Waste Disposal

Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Under 40 CFR 261.5 small quantity generators of this waste may qualify for partial exclusion from hazardous waste regulations.

Properties of N-NITROSOPIPERIDINE

Melting point: 170℃ (decomposition)
Boiling point: 219℃
Density  1.06 g/mL(lit.)
refractive index  1.4933 (589.3 nm 19℃)
Flash point: 11 °C
storage temp.  2-8°C
solubility  Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka -3.18±0.20(Predicted)
form  buffered aqueous solution
color  Light-yellow oil
Water Solubility  76.48g/L(24 ºC)
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
CAS DataBase Reference 100-75-4(CAS DataBase Reference)
IARC 2B (Vol. 17, Sup 7) 1987
EPA Substance Registry System N-Nitrosopiperidine (100-75-4)

Safety information for N-NITROSOPIPERIDINE

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Skull and Crossbones
Acute Toxicity
GHS06
ghs
Health Hazard
GHS08
GHS Hazard Statements H225:Flammable liquids
H370:Specific target organ toxicity, single exposure
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P311:Call a POISON CENTER or doctor/physician.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Computed Descriptors for N-NITROSOPIPERIDINE

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