N-METHYLSUCCINIMIDE
- CAS NO.：1121-07-9
- Empirical Formula: C5H7NO2
- Molecular Weight: 113.11
- MDL number: MFCD00005517
- EINECS: 628-414-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:34
What is N-METHYLSUCCINIMIDE?
Chemical properties
white crystals
The Uses of N-METHYLSUCCINIMIDE
N-Methylsuccinimide is used as a model compound to investigate the mechanism of enolization step by density-functional theory (DFT) calculations. N-Methylsuccinimide is a metabolite of N-methyl-2-pyrrolidone (NMP) and its presence in plasma and urine can be used as a biomarker of exposure to NMP
What are the applications of Application
N-Methylsuccinimide is a model compound to investigate the mechanism of enolization step by density-functional theory (DFT) calculations
Synthesis Reference(s)
Chemical and Pharmaceutical Bulletin, 31, p. 4209, 1983 DOI: 10.1248/cpb.31.4209
General Description
N-Methylsuccinimide is a metabolite of N-methyl-2-pyrrolidone (NMP) and its presence in in plasma and urine can be used as a biomarker of exposure to NMP. Hydrogen bonded complexes between N-methylsuccinimide and phenols (pKa = 10.2 → 6) are investigated by infrared spectrometry.
Properties of N-METHYLSUCCINIMIDE
| Melting point: | 61-70 °C(lit.) |
| Boiling point: | 234-235 °C(lit.) |
| Density | 1.2416 (rough estimate) |
| refractive index | 1.4790 (estimate) |
| Flash point: | 234-235°C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | -1.34±0.20(Predicted) |
| color | Off-White |
| Sensitive | Moisture Sensitive |
| BRN | 110534 |
| CAS DataBase Reference | 1121-07-9(CAS DataBase Reference) |
Safety information for N-METHYLSUCCINIMIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-METHYLSUCCINIMIDE
New Products
Tubulysin G Tubulysin I Tubulysin F 2,2,6,6-tetramethyl-2H-3,5,6-trihydropyran-4-one 1-(1,1-Difluoroethyl)-2-fluorobenzene 2,2-Difluoropropanol (S)-(+)-3-HYDROXYTETRAHYDROFURAN tetrahydro-4-methyl-2H-pyran (R)-1-BOC-3-FLUORO PYRROLIDINE (R)-1-Aminoindan Hydrochloride 2,3-Dichloro-6- nitrobenzylamine Hydrochloride 4-(2-fluoro-4- nitrophenyl) thiomorpholine 2-(2,3-Dihydro- benzofuran-5-yl)-1- morpholin-4-yl- ethanethione 4-N-Methylamino- 3-nitro benzoic acid 3-(S)-(+)- (-1-carbamoyl-1, 1-diphenylmethyl)- pyrrolidine-L- tartarate 7-Methoxyquinoline-4-carbonitrile 1H-Imidazole-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acid Methyl (2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoate (R)-methyl 2-formamido-3-(tritylthio)propanoate (R)-methyl 2-isocyano-3-(tritylthio)propanoate Salbutamol EP Impurity K / Salbutamol BP Impurity K Sertraline EP Impurity B / Sertraline BP Impurity B / 3,4-Dideschloro Sertraline HCl (USP) / cis-3,4-Dideschloro Sertraline HCl / Sertraline Phenyl Impurity HALOPERIDOL DECANOATE EP IMPURITY J | HALOPERIDOL UNDECANOATERelated products of tetrahydrofuran
You may like
-
N-Methylsuccinimide CAS 1121-07-9View Details
1121-07-9 -
n-Methylsuccinimide, 99% CAS 1121-07-9View Details
1121-07-9 -
N-Methylsuccinimide 98.00% CAS 1121-07-9View Details
1121-07-9 -
N-Methylsuccinimide CAS 1121-07-9View Details
1121-07-9 -
3-(4-Chloro-butyryl) -1H-indole-5- carbonitrileView Details
276863-95-7 -
Ethyl 5-Aminobenzofuran-2- CarboxylateView Details
174775-48-5 -
(2,3-Dihydro- benzofuran-5-yl)- ethanolView Details
87776-76-9 -
2,3-dichloro-6- nitrobenzonitrileView Details
2112-23-2
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.