N-HYDROXYBUTYRAMIDINE
- CAS NO.：27620-10-6
- Empirical Formula: C4H10N2O
- Molecular Weight: 102.14
- MDL number: MFCD05663152
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-16 08:28:57
What is N-HYDROXYBUTYRAMIDINE?
Description
N-hydroxybutyramidine is a kind of pharmaceutical intermediate, which can be prepared by the reaction of butyronitrile and hydroxylamine hydrochloride. It has been reported in the literature that it can be used to prepare (PI3) inhibitors.
What are the applications of Application
N-hydroxybutyramidine is an organic synthesis intermediate and a pharmaceutical intermediate, which can be used in the laboratory research and development process and the chemical and pharmaceutical synthesis process.
Preparation
A solution of a mixture of butyronitrile, NaOH and hydroxylamine hydrochloride in 95% ethanol and water was refluxed Heat for 12 hours. The solvent was removed in vacuo, the oily residue was dissolved in chloroform , and insoluble NaCl was removed by filtration. The filtrate was concentrated in vacuo to give N-hydroxybutyramidine as a colorless oil.
Properties of N-HYDROXYBUTYRAMIDINE
| Boiling point: | 89 °C |
| color | Pale brown |
| CAS DataBase Reference | 27620-10-6 |
Safety information for N-HYDROXYBUTYRAMIDINE
| Signal word | Danger |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-HYDROXYBUTYRAMIDINE
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