N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE
Synonym(s):Heptyl thioglucoside;Heptyl-β-D -1-thioglucopyranoside
- CAS NO.：85618-20-8
- Empirical Formula: C13H26O5S
- Molecular Weight: 294.41
- MDL number: MFCD00043236
- EINECS: 1533716-785-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
What is N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE?
Chemical properties
White Paste
The Uses of N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE
n-Heptyl β-D-thioglucopyranoside is useful non-ionic detergent for solubilization and reconstitution of membrane proteins of Escherichia coli.
Purification Methods
The tetraacetyl derivative is purified by silica gel column chromatography and eluted with a *C6H6/Me2CO gradient (up to 5% of Me2CO) and recrystallises from n-hexane as colourless needles m 72-74o (Erbing & Lindberg Acta Chem Scand B30 611 1976 gave m 69-70o). Hydrolysis with an equivalent of base in methanol gives the desired glucoside. This is a non-ionic detergent for reconstituting membrane proteins and has a critical micelle concentration of 30 mM. [Shimamoto et al. J Biochem (Tokyo) 97 1807 1985; Saito & Tsuchiya Chem Pharm Bull Jpn 33 503 1985].
Properties of N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE
| Melting point: | 96.1-98.3°C |
| Boiling point: | 479.9±45.0 °C(Predicted) |
| Density | 1.23±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | methanol: 0.1 g/mL, clear, yellow |
| form | Solid |
| pka | 13.02±0.70(Predicted) |
| color | White Waxy |
| BRN | 6057483 |
| CAS DataBase Reference | 85618-20-8(CAS DataBase Reference) |
Safety information for N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE
Computed Descriptors for N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE
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