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HomeProduct name listN-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE

N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE

Synonym(s):Heptyl thioglucoside;Heptyl-β-D-1-thioglucopyranoside

  • CAS NO.:85618-20-8
  • Empirical Formula: C13H26O5S
  • Molecular Weight: 294.41
  • MDL number: MFCD00043236
  • EINECS: 1533716-785-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-04-23 13:52:06
N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE Structural

What is N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE?

Chemical properties

White Paste

The Uses of N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE

n-Heptyl β-D-thioglucopyranoside is useful non-ionic detergent for solubilization and reconstitution of membrane proteins of Escherichia coli.

Purification Methods

The tetraacetyl derivative is purified by silica gel column chromatography and eluted with a *C6H6/Me2CO gradient (up to 5% of Me2CO) and recrystallises from n-hexane as colourless needles m 72-74o (Erbing & Lindberg Acta Chem Scand B30 611 1976 gave m 69-70o). Hydrolysis with an equivalent of base in methanol gives the desired glucoside. This is a non-ionic detergent for reconstituting membrane proteins and has a critical micelle concentration of 30 mM. [Shimamoto et al. J Biochem (Tokyo) 97 1807 1985; Saito & Tsuchiya Chem Pharm Bull Jpn 33 503 1985].

Properties of N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE

Melting point: 96.1-98.3°C
Boiling point: 479.9±45.0 °C(Predicted)
Density  1.23±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  methanol: 0.1 g/mL, clear, yellow
form  Solid
pka 13.02±0.70(Predicted)
color  White Waxy
BRN  6057483
CAS DataBase Reference 85618-20-8(CAS DataBase Reference)

Safety information for N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE

Computed Descriptors for N-HEPTYL-BETA-D-THIOGLUCOPYRANOSIDE

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