N-ETHYL-N-(2-HYDROXYETHYL)NITROSAMINE

The Uses of N-ETHYL-N-(2-HYDROXYETHYL)NITROSAMINE

N-Ethyl-N-(2-hydroxyethyl)nitrosamine is a member of the nitrosamine class of carcinogens and induces renal cancer. It has been shown to induce tumors in the kidneys of rats and in the lungs of mice.

Definition

ChEBI: N-ethyl-N-(2-hydroxyethyl)nitrosamine is a nitrosamine that is N-nitrosodiethylamine in which one of the ethyl froups has been replaced by a 2-hydroxyethyl group. It is used to induce renal and liver tumours in rodents. It has a role as a carcinogenic agent. It is a nitrosamine and a primary alcohol. It is functionally related to a N-nitrosodiethylamine.

Safety Profile

Suspected carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Mutation data reported. Explodes when heated to 170℃. When heated to decomposition it emits toxic fumes of NOx. See also NITROSAMINES.