N-Cbz-L-Leucine
Synonym(s):N-(Benzyloxycarbonyl)leucine;N-(Benzyloxycarbonyl)-L-leucine;N-(Carbobenzoxy)leucine;N-(Phenylmethoxy)carbonyl-L-leucine;N-Carbobenzoxy-L-leucine
- CAS NO.：2018-66-8
- Empirical Formula: C14H19NO4
- Molecular Weight: 265.3
- MDL number: MFCD00026494
- EINECS: 217-960-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-12-18 14:20:06
What is N-Cbz-L-Leucine?
Chemical properties
yellow oil or weak solid
The Uses of N-Cbz-L-Leucine
Reactant for:
- Peptide-based preparation of potential antitumor agents
- Preparation of cyclopropyl peptidomimetics
- Peptide synthesis
Definition
ChEBI: A L-leucine derivative obtained by the substitution of a benzyloxycarbonyl group on the nitrogen atom.
Properties of N-Cbz-L-Leucine
| Boiling point: | 408.52°C (rough estimate) |
| alpha | -17 º (c=2, ethanol) |
| Density | 1 g/mL at 25 °C(lit.) |
| refractive index | n |
| Flash point: | 85 °F |
| storage temp. | Sealed in dry,2-8°C |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | viscous liquid |
| pka | 4.00±0.21(Predicted) |
| Specific Gravity | 1.0 |
| color | Colorless to Light yellow |
| optical activity | [α]20/D 17°, c = 2 in ethanol |
| Water Solubility | Not miscible or difficult to mix in water. Soluble in chloroform, DMSO and methanol. |
| BRN | 1253861 |
| CAS DataBase Reference | 2018-66-8(CAS DataBase Reference) |
Safety information for N-Cbz-L-Leucine
| Signal word | Warning |
| Pictogram(s) |
 Flame Flammables GHS02  Health Hazard GHS08 |
| GHS Hazard Statements |
H226:Flammable liquids H351:Carcinogenicity |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P370+P378:In case of fire: Use … for extinction. |
Computed Descriptors for N-Cbz-L-Leucine
Abamectin manufacturer
ADVENT CHEMBIO PRIVATE LIMITED
1Y
Phone:+919821524116
Whatsapp: +91 9821524116
product: 2018-66-8 N-Cbz-L-leucine, 97% [Z-Leu-OH] 98%
TEADUS PHARMA PRIVATE LIMITED
1Y
Phone:+91-9740077663
Whatsapp: +91 9740077663
product: 2018-66-6 95%
SV CHEM INTERMEDITES PRIVATE LIMITED
1Y
Phone:+91-9940629423
Whatsapp: +91 9940629423
product: CBZ-L-Leucine 99%
Khagga Life Sciences
1Y
Phone:+91-9603316441
Whatsapp: +91 8885386544
product: N-Cbz-L-Leucine 2018-66-8 98%
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