N-Benzyloxycarbonyl-L-asparagine

Synonym(s):Z-L-Asparagine

CAS NO.：2304-96-3
Empirical Formula: C12H14N2O5
Molecular Weight: 266.25
MDL number: MFCD00008035
EINECS: 218-969-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-05-16 10:38:43

N-Benzyloxycarbonyl-L-asparagine Structural

What is N-Benzyloxycarbonyl-L-asparagine?

Chemical properties

white to light yellow crystal powde

The Uses of N-Benzyloxycarbonyl-L-asparagine

Nα-Cbz-L-asparagine is an N-Cbz-protected form of L-Asparagine (A790005). L-Asparagine was first isolated by Robiquet and Vauquelin from asparagus juice (a high source of L-asparagine). L-Asparagine is often incorporated into proteins, and is a basis for some cancer therapies as certain cancerous cells require L-asparagine for growth.

Properties of N-Benzyloxycarbonyl-L-asparagine

Melting point:	163-165 °C(lit.)
Boiling point:	409.45°C (rough estimate)
alpha	6.5 º (c=2, CH3COOH)
Density	1.2846 (rough estimate)
refractive index	6.3 ° (C=1.6, AcOH)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	almost transparency in hot Methanol
form	powder to crystal
pka	3.77±0.10(Predicted)
color	White to Almost white
optical activity	[α]20/D +6°, c = 1.6 in acetic acid
BRN	3085452
CAS DataBase Reference	2304-96-3(CAS DataBase Reference)
EPA Substance Registry System	L-Asparagine, N2-[(phenylmethoxy)carbonyl]- (2304-96-3)

Safety information for N-Benzyloxycarbonyl-L-asparagine

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water.