N-Benzyl-N-methylethanolamine
Synonym(s):2-(N-Benzyl-N-methylamino)ethanol
- CAS NO.:101-98-4
- Empirical Formula: C10H15NO
- Molecular Weight: 165.23
- MDL number: MFCD00002847
- EINECS: 202-994-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:30
What is N-Benzyl-N-methylethanolamine?
Description
N-Benzyl-N-methylethanolamine is a surfactant that has a high capacity for adsorbing proteins. It is used as an efficient method to remove impurities from human immunoglobulin preparations and as an adsorbent in chromatographic methods. N-Benzyl-N-methylethanolamine has also been used as a diagnostic agent for the detection of chromatographically separated monoclonal antibodies, which are produced by activated B cells in culture. The antibody binds to the target protein and then the antibody-protein complex is isolated using a particle agglomeration technique. This method can be repeated multiple times and produce high concentrations of pure monoclonal antibodies.
Chemical properties
clear yellowish liquid
The Uses of N-Benzyl-N-methylethanolamine
2-[Methyl(phenylmethyl)amino]ethanol is used in the preparation of dihydropyrimidinones as sodium iodide symporter inhibitors used to regulate the accumulation of iodide in the thyroid gland. Also used in the synthesis of new class of pseudopeptides as potential inhibitors of β-sheet aggregation.
What are the applications of Application
N-Benzyl-N-methylethanolamine is a tertiary benzylamine
General Description
N-Benzyl-N-methylethanolamine is a tertiary benzylamine. Electrochemical alkoxylation of N-benzyl-N-methylethanolamine is reported. Rate of proton exchange of N-benzyl-N-methylethanolamine in aqueous HCl has been reported.
Properties of N-Benzyl-N-methylethanolamine
Boiling point: | 95-105 °C2 mm Hg(lit.) |
Density | 1.017 g/mL at 25 °C(lit.) |
refractive index | n |
Flash point: | >230 °F |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Oil |
pka | 14.75±0.10(Predicted) |
color | Colourless |
BRN | 366412 |
CAS DataBase Reference | 101-98-4(CAS DataBase Reference) |
NIST Chemistry Reference | Ethanol, 2-[methyl(phenylmethyl)amino]-(101-98-4) |
EPA Substance Registry System | Ethanol, 2-[methyl(phenylmethyl)amino]- (101-98-4) |
Safety information for N-Benzyl-N-methylethanolamine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-Benzyl-N-methylethanolamine
N-Benzyl-N-methylethanolamine manufacturer
CNS CHEMICALS
Cns Chemicals
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