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HomeProduct name listN-Benzyl-N-methylethanolamine

N-Benzyl-N-methylethanolamine

Synonym(s):2-(N-Benzyl-N-methylamino)ethanol

  • CAS NO.:101-98-4
  • Empirical Formula: C10H15NO
  • Molecular Weight: 165.23
  • MDL number: MFCD00002847
  • EINECS: 202-994-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-05-28 19:59:05
N-Benzyl-N-methylethanolamine Structural

What is N-Benzyl-N-methylethanolamine?

Description

N-Benzyl-N-methylethanolamine is a surfactant that has a high capacity for adsorbing proteins. It is used as an efficient method to remove impurities from human immunoglobulin preparations and as an adsorbent in chromatographic methods. N-Benzyl-N-methylethanolamine has also been used as a diagnostic agent for the detection of chromatographically separated monoclonal antibodies, which are produced by activated B cells in culture. The antibody binds to the target protein and then the antibody-protein complex is isolated using a particle agglomeration technique. This method can be repeated multiple times and produce high concentrations of pure monoclonal antibodies.

Chemical properties

clear yellowish liquid

The Uses of N-Benzyl-N-methylethanolamine

2-[Methyl(phenylmethyl)amino]ethanol is used in the preparation of dihydropyrimidinones as sodium iodide symporter inhibitors used to regulate the accumulation of iodide in the thyroid gland. Also used in the synthesis of new class of pseudopeptides as potential inhibitors of β-sheet aggregation.

What are the applications of Application

N-Benzyl-N-methylethanolamine is a tertiary benzylamine

General Description

N-Benzyl-N-methylethanolamine is a tertiary benzylamine. Electrochemical alkoxylation of N-benzyl-N-methylethanolamine is reported. Rate of proton exchange of N-benzyl-N-methylethanolamine in aqueous HCl has been reported.

Properties of N-Benzyl-N-methylethanolamine

Boiling point: 95-105 °C2 mm Hg(lit.)
Density  1.017 g/mL at 25 °C(lit.)
refractive index  n20/D 1.529(lit.)
Flash point: >230 °F
storage temp.  Sealed in dry,Room Temperature
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Oil
pka 14.75±0.10(Predicted)
color  Colourless
BRN  366412
CAS DataBase Reference 101-98-4(CAS DataBase Reference)
NIST Chemistry Reference Ethanol, 2-[methyl(phenylmethyl)amino]-(101-98-4)
EPA Substance Registry System Ethanol, 2-[methyl(phenylmethyl)amino]- (101-98-4)

Safety information for N-Benzyl-N-methylethanolamine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for N-Benzyl-N-methylethanolamine

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