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HomeProduct name listN-Acetyl-L-leucine

N-Acetyl-L-leucine

  • CAS NO.:1188-21-2
  • Empirical Formula: C8H15NO3
  • Molecular Weight: 173.21
  • MDL number: MFCD00065131
  • EINECS: 214-706-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-06 15:28:16
N-Acetyl-L-leucine Structural

What is N-Acetyl-L-leucine?

Chemical properties

White crystalline powder

The Uses of N-Acetyl-L-leucine

N-Acetyl-L-(-)-leucine is used in the preparation of small molecule inhibitors of anti-apoptotic Bcl-2 family proteins. Also used in the preparation of amphiphilic copolymers involving hydrophobic amino acid and oligopeptide side chains for optical tumor imaging in vivo.

What are the applications of Application

N-Acetyl-L-leucine is a derivative of L-leucine carrying an N-acylated aliphatic chain

Definition

ChEBI: The N-acetyl derivative of L-leucine.

Properties of N-Acetyl-L-leucine

Melting point: 187-190 °C(lit.)
Boiling point: 303.86°C (rough estimate)
alpha  -24.5 º (c=4, MeOH)
Density  1.1599 (rough estimate)
refractive index  -22 ° (C=5, EtOH)
storage temp.  Sealed in dry,Room Temperature
solubility  DMSO (Slightly), Ethanol (Slightly), Water (Slightly, Heated)
form  Crystalline Powder
pka 3.67±0.10(Predicted)
color  White
optical activity [α]25/D 23±3°, c = 2 in ethanol
Water Solubility  0.81 g/100 mL (20 ºC)
BRN  1724849
CAS DataBase Reference 1188-21-2(CAS DataBase Reference)
NIST Chemistry Reference L-leucine, n-acetyl-(1188-21-2)
EPA Substance Registry System L-Leucine, N-acetyl- (1188-21-2)

Safety information for N-Acetyl-L-leucine

Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for N-Acetyl-L-leucine

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