N-(3-AMINOPROPYL) METHACRYLAMIDE

Synonym(s):APMA

CAS NO.：72607-53-5
Empirical Formula: C7H15ClN2O
Molecular Weight: 178.66
MDL number: MFCD00078257
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

N-(3-AMINOPROPYL) METHACRYLAMIDE Structural

What is N-(3-AMINOPROPYL) METHACRYLAMIDE?

The Uses of N-(3-AMINOPROPYL) METHACRYLAMIDE

APMA can be used in the preparation of copolymers and cross-linked miscellas for gene delivery, drug delivery and diagnostics applications.

General Description

N-(3-Aminopropyl)methacrylamide hydrochloride (APMA) is an aminoalkyl methacrylamide which can be synthesized by adding 1,3-diaminopropane to 1,3-diaminopropane dihydrogen chloride solution and further mixing the solution with methacrylic anhydride and hydroquinone. It has a primary amine that provides attractive features such as pH-responsiveness, affinity for anionic drugs and conjugation for variety of chemical structures.

Properties of N-(3-AMINOPROPYL) METHACRYLAMIDE

Melting point:	123-128°C
storage temp.	2-8°C
form	powder
EPA Substance Registry System	2-Propenamide, N-(3-aminopropyl)-2-methyl-, monohydrochloride (72607-53-5)

Safety information for N-(3-AMINOPROPYL) METHACRYLAMIDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P337+P313:IF eye irritation persists: Get medical advice/attention.