N-(1-PYRENYL)MALEIMIDE
Synonym(s):1-(1-Pyrenyl)-1H-pyrrole-2,5-dione
- CAS NO.：42189-56-0
- Empirical Formula: C20H11NO2
- Molecular Weight: 297.31
- MDL number: MFCD00049301
- EINECS: 255-702-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 17:06:38
What is N-(1-PYRENYL)MALEIMIDE?
Chemical properties
N-(1-PYRENYL)MALEIMIDE is Yellow Solid
The Uses of N-(1-PYRENYL)MALEIMIDE
N-(1-PYRENYL)MALEIMIDE is a fluorescent sulfhydryl reagent that can form excited-state dimers which emit at longer wavelenghts than the lone excited fluorophore.
The Uses of N-(1-PYRENYL)MALEIMIDE
Reactant used in synthesis of: • ;Oligodeoxynucleotide derivatives1 • ;Polymer conjugates of immunogenic peptides2 • ;Modified oligonucleotides for biosensing applications3,Reactant: • ;Involved in synthesis of thermally stable fluorescent maleimide/isobutene alternating copolymers4• ;Used as derivitizing agent for determination of glutathione disulfide levels in biological samples5
What are the applications of Application
N-(1-Pyrenyl) Maleimide is a florescent sulfhydryl reagent
Properties of N-(1-PYRENYL)MALEIMIDE
| Melting point: | 235-237 °C(lit.) |
| Boiling point: | 438.82°C (rough estimate) |
| Density | 1.2310 (rough estimate) |
| refractive index | 1.5180 (estimate) |
| storage temp. | Refrigerator |
| solubility | Soluble in chloroform, N,Ndimethylformamide, dimethyl sulfoxide, ethanol, methanol |
| form | Solid |
| pka | –1.21±0.20, most basic, temperature: 25°C |
| color | Yellow needles;Gold needles |
| λmax | 338nm, 325nm (MeOH) |
| BRN | 1542661 |
| Major Application | Dendrimers; dye functionalized single-wall carbon nanotube (SWNT) conjugated polymer devices; photovoltaic cells; polymer-coated gold electrodes; fluorescent polymers; radio-fluorogenic gel; in sequencecontrolled polymerizations; rubber |
| Biological Applications | Analyzing molecular aspects of muscle contraction; detecting nucleic acids, proteins; determining/evaluating cell activity; diagnosing/treating Parkinson’s disease; monitoring/studying ribosomal structure and conformation; studying nicotinic acetylcholine receptor (AChR) structure; sulfhydryl reagent |
| CAS DataBase Reference | 42189-56-0(CAS DataBase Reference) |
Safety information for N-(1-PYRENYL)MALEIMIDE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for N-(1-PYRENYL)MALEIMIDE
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