N-(1-PYRENYL)MALEIMIDE

Synonym(s):1-(1-Pyrenyl)-1H-pyrrole-2,5-dione

CAS NO.：42189-56-0
Empirical Formula: C20H11NO2
Molecular Weight: 297.31
MDL number: MFCD00049301
EINECS: 255-702-1
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:38

What is N-(1-PYRENYL)MALEIMIDE?

Chemical properties

N-(1-PYRENYL)MALEIMIDE is Yellow Solid

The Uses of N-(1-PYRENYL)MALEIMIDE

N-(1-PYRENYL)MALEIMIDE is a fluorescent sulfhydryl reagent that can form excited-state dimers which emit at longer wavelenghts than the lone excited fluorophore.

The Uses of N-(1-PYRENYL)MALEIMIDE

Reactant used in synthesis of: • ;Oligodeoxynucleotide derivatives1 • ;Polymer conjugates of immunogenic peptides2 • ;Modified oligonucleotides for biosensing applications3,Reactant: • ;Involved in synthesis of thermally stable fluorescent maleimide/isobutene alternating copolymers4• ;Used as derivitizing agent for determination of glutathione disulfide levels in biological samples5

What are the applications of Application

N-(1-Pyrenyl) Maleimide is a florescent sulfhydryl reagent

Properties of N-(1-PYRENYL)MALEIMIDE

Melting point:	235-237 °C(lit.)
Boiling point:	438.82°C (rough estimate)
Density	1.2310 (rough estimate)
refractive index	1.5180 (estimate)
storage temp.	Refrigerator
solubility	Soluble in chloroform, N,Ndimethylformamide, dimethyl sulfoxide, ethanol, methanol
form	Solid
pka	–1.21±0.20, most basic, temperature: 25°C
color	Yellow needles;Gold needles
λmax	338nm, 325nm (MeOH)
BRN	1542661
Major Application	Dendrimers; dye functionalized single-wall carbon nanotube (SWNT) conjugated polymer devices; photovoltaic cells; polymer-coated gold electrodes; fluorescent polymers; radio-fluorogenic gel; in sequencecontrolled polymerizations; rubber
Biological Applications	Analyzing molecular aspects of muscle contraction; detecting nucleic acids, proteins; determining/evaluating cell activity; diagnosing/treating Parkinson’s disease; monitoring/studying ribosomal structure and conformation; studying nicotinic acetylcholine receptor (AChR) structure; sulfhydryl reagent
CAS DataBase Reference	42189-56-0(CAS DataBase Reference)

Safety information for N-(1-PYRENYL)MALEIMIDE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.