methylnaltrexone

CAS NO.：83387-25-1
Empirical Formula: C21H26NO4+
Molecular Weight: 356.43544
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-04 17:34:43

What is methylnaltrexone?

definition

ChEBI: Methylnaltrexone is a member of phenanthrenes.

General Description

Methylnaltrexone (Relistor) is the methylated, quaternaryform of naltrexone . The permanently chargednitrogen prevents the drug from crossing the blood-brainbarrier. Thus, it only acts as an antagonist at peripheralopioid receptors. Relistor was approved in April 2008 totreat opioid-induced constipation in patients receiving palliativecare. It is administered as a SC injection once everyother day.

Safety information for methylnaltrexone

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