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HomeProduct name listMethyl indolyl-3-glyoxylate

Methyl indolyl-3-glyoxylate

Synonym(s):Methyl 2-(indol-3-yl)-2-oxoacetate

Methyl indolyl-3-glyoxylate Structural

What is Methyl indolyl-3-glyoxylate?

Chemical properties

Pale Yellow Fine Powder

The Uses of Methyl indolyl-3-glyoxylate

Methyl Indolyl-3-glyoxylate (cas# 18372-22-0) is a compound useful in organic synthesis.

The Uses of Methyl indolyl-3-glyoxylate

Reactant for preparation of sotrastaurin analogs as protein kinase inhibitors 1 Reactant for synthesis of GSK-3 inhibitors 2 Reactant for Diels-Alder cycloaddition 3 Reactant for preparation of a Janus kinase 3 inhibitor 4 Reactant for synthesis of cephalandole alkaloids 5 Reactant for stereoselective preparation of COX-2 inhibitor as anticancer agent 6 Reactant for synthesis of cycloalkene indole carbazole alkaloids via ring-closing metathesis.

Properties of Methyl indolyl-3-glyoxylate

Melting point: 227-230 °C (lit.)
Boiling point: 383.2±15.0 °C(Predicted)
Density  1.324±0.06 g/cm3(Predicted)
storage temp.  Sealed in dry,Room Temperature
solubility  Acetone, Methanol
form  Solid
pka 14.54±0.30(Predicted)
color  Pale Yellow Fine
Stability: Temperature Sensitive
CAS DataBase Reference 18372-22-0(CAS DataBase Reference)

Safety information for Methyl indolyl-3-glyoxylate

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Methyl indolyl-3-glyoxylate

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