METHYL ARACHIDONATE
Synonym(s):Arachidonic acid methyl ester
- CAS NO.:2566-89-4
- Empirical Formula: C21H34O2
- Molecular Weight: 318.49
- MDL number: MFCD00016775
- EINECS: 219-900-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 16:48:35
What is METHYL ARACHIDONATE?
The Uses of METHYL ARACHIDONATE
Arachidonic acid is the keystone essential fatty acid at the origin of the arachidonic acid cascade. It is converted by cyclooxygenase, lipoxygenase, and epoxygenase enzymes into more than one hundred fifty different potent primary autacoid metabolites in species ranging from fungi to plants to mammals. Arachidonic acid is stored in tissue phospholipids in esterified form, where it comprises a small but critically controlled percentage of the polyunsaturated fatty acid pool. Arachidonic acid content is frequently measured by the saponification of the lipid fraction followed by methyl esterification and gas chromatographic analysis of the resulting FAME (fatty acid methyl ester) compounds. Arachidonic acid methyl ester can also be incorporated into dietary regimens or fed to cultured cells as a source of exogenous arachidonate.
What are the applications of Application
Arachidonic Acid methyl ester is the keystone essential fatty acid at the origin of the arachidonic acid cascade
Definition
ChEBI: A fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol.
Biochem/physiol Actions
Unlike most unsaturated fatty acid methyl esters, methyl arachidonate is a potent activator of protein kinase C at 5?50?μM. At the low end of the effective concentration range, the effect is due to cyclooxygenase products, while lipoxygenase products mediate the effect at higher concentrations.
Properties of METHYL ARACHIDONATE
Boiling point: | 200-205℃ (1-2 Torr) |
Density | 0.9168 g/cm3 |
refractive index | 1.4875 (589.3 nm 20℃) |
storage temp. | 2-8°C |
solubility | chloroform: 50 mg/mL, clear, colorless |
form | Liquid |
color | Colourless |
BRN | 1714445 |
Stability: | Light Sensitive |
Safety information for METHYL ARACHIDONATE
Signal word | Danger |
Pictogram(s) |
Exclamation Mark Irritant GHS07 Health Hazard GHS08 Environment GHS09 |
GHS Hazard Statements |
H304:Aspiration hazard H315:Skin corrosion/irritation H336:Specific target organ toxicity,single exposure; Narcotic effects H410:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P331:Do NOT induce vomiting. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P501:Dispose of contents/container to..… |
Computed Descriptors for METHYL ARACHIDONATE
New Products
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