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HomeProduct name listMETHYL ARACHIDONATE

METHYL ARACHIDONATE

Synonym(s):Arachidonic acid methyl ester

  • CAS NO.:2566-89-4
  • Empirical Formula: C21H34O2
  • Molecular Weight: 318.49
  • MDL number: MFCD00016775
  • EINECS: 219-900-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-28 16:48:35
METHYL ARACHIDONATE Structural

What is METHYL ARACHIDONATE?

The Uses of METHYL ARACHIDONATE

Arachidonic acid is the keystone essential fatty acid at the origin of the arachidonic acid cascade. It is converted by cyclooxygenase, lipoxygenase, and epoxygenase enzymes into more than one hundred fifty different potent primary autacoid metabolites in species ranging from fungi to plants to mammals. Arachidonic acid is stored in tissue phospholipids in esterified form, where it comprises a small but critically controlled percentage of the polyunsaturated fatty acid pool. Arachidonic acid content is frequently measured by the saponification of the lipid fraction followed by methyl esterification and gas chromatographic analysis of the resulting FAME (fatty acid methyl ester) compounds. Arachidonic acid methyl ester can also be incorporated into dietary regimens or fed to cultured cells as a source of exogenous arachidonate.

What are the applications of Application

Arachidonic Acid methyl ester is the keystone essential fatty acid at the origin of the arachidonic acid cascade

Definition

ChEBI: A fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol.

Biochem/physiol Actions

Unlike most unsaturated fatty acid methyl esters, methyl arachidonate is a potent activator of protein kinase C at 5?50?μM. At the low end of the effective concentration range, the effect is due to cyclooxygenase products, while lipoxygenase products mediate the effect at higher concentrations.

Properties of METHYL ARACHIDONATE

Boiling point: 200-205℃ (1-2 Torr)
Density  0.9168 g/cm3
refractive index  1.4875 (589.3 nm 20℃)
storage temp.  2-8°C
solubility  chloroform: 50 mg/mL, clear, colorless
form  Liquid
color  Colourless
BRN  1714445
Stability: Light Sensitive

Safety information for METHYL ARACHIDONATE

Signal word Danger
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
ghs
Environment
GHS09
GHS Hazard Statements H304:Aspiration hazard
H315:Skin corrosion/irritation
H336:Specific target organ toxicity,single exposure; Narcotic effects
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P273:Avoid release to the environment.
P331:Do NOT induce vomiting.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P501:Dispose of contents/container to..…

Computed Descriptors for METHYL ARACHIDONATE

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