Methyl 3-broMo-6-chloropyrazine-2-carboxylate
- CAS NO.：13457-28-8
- Empirical Formula: C6H4BrClN2O2
- Molecular Weight: 251.47
- MDL number: MFCD13195362
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-02-18 15:10:22
What is Methyl 3-broMo-6-chloropyrazine-2-carboxylate?
The Uses of Methyl 3-broMo-6-chloropyrazine-2-carboxylate
Methyl 3-broMo-6-chloropyrazine-2-carboxylate is an important intermediate for the synthesis of a class of antitumour drugs, SHP2 inhibitors, which can be used in the pharmaceutical development process.
Properties of Methyl 3-broMo-6-chloropyrazine-2-carboxylate
| Melting point: | 35-36 °C |
| Boiling point: | 292.4±35.0 °C(Predicted) |
| Density | 1.772±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| pka | -3.78±0.10(Predicted) |
Safety information for Methyl 3-broMo-6-chloropyrazine-2-carboxylate
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H227:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. P370+P378:In case of fire: Use … for extinction. P403+P235:Store in a well-ventilated place. Keep cool. |
Computed Descriptors for Methyl 3-broMo-6-chloropyrazine-2-carboxylate
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