marinobufagenin
- CAS NO.：470-42-8
- Empirical Formula: C24H32O5
- Molecular Weight: 400.52
- MDL number: MFCD32661898
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-26 17:49:17
What is marinobufagenin?
The Uses of marinobufagenin
Marinobufagin is a bufadienolide with anti-gastric cancer effect. A bioactive steroid that also functions as an endogenous Na/K-ATPase bufadienolide inhibitor that plays a major role in human cardiovascular diseases.
Definition
ChEBI: Marinobufagenin is a cardiotonic steroid secreted by the toad Bufo rubescens and other related species such as Bufo marinus. An endogenous Na/K-ATPase inhibitor, it is a vasoconstrictor with effects similar to digitalis. It has a role as an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor and an epitope. It is a steroid hormone and an epoxy steroid. It is functionally related to a (5beta)-bufadienolide.
Properties of marinobufagenin
| Melting point: | 224-225 °C |
| Boiling point: | 589.0±50.0 °C(Predicted) |
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 3 mg/ml; DMF:PBS (pH 7.2) (1:8): 0.1 mg/ml; Ethanol: 1 mg/ml |
| form | A crystalline solid |
| pka | 14.77±0.70(Predicted) |
| color | White to off-white |
Safety information for marinobufagenin
Computed Descriptors for marinobufagenin
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