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HomeProduct name listmarinobufagenin

marinobufagenin

  • CAS NO.:470-42-8
  • Empirical Formula: C24H32O5
  • Molecular Weight: 400.52
  • MDL number: MFCD32661898
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-07-26 17:49:17
marinobufagenin Structural

What is marinobufagenin?

The Uses of marinobufagenin

Marinobufagin is a bufadienolide with anti-gastric cancer effect. A bioactive steroid that also functions as an endogenous Na/K-ATPase bufadienolide inhibitor that plays a major role in human cardiovascular diseases.

Definition

ChEBI: Marinobufagenin is a cardiotonic steroid secreted by the toad Bufo rubescens and other related species such as Bufo marinus. An endogenous Na/K-ATPase inhibitor, it is a vasoconstrictor with effects similar to digitalis. It has a role as an EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor and an epitope. It is a steroid hormone and an epoxy steroid. It is functionally related to a (5beta)-bufadienolide.

Properties of marinobufagenin

Melting point: 224-225 °C
Boiling point: 589.0±50.0 °C(Predicted)
Density  1.31±0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  DMF: 3 mg/ml; DMF:PBS (pH 7.2) (1:8): 0.1 mg/ml; Ethanol: 1 mg/ml
form  A crystalline solid
pka 14.77±0.70(Predicted)
color  White to off-white

Safety information for marinobufagenin

Computed Descriptors for marinobufagenin

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