LEVCROMAKALIM
- CAS NO.：94535-50-9
- Empirical Formula: C16H18N2O3
- Molecular Weight: 286.33
- MDL number: MFCD00864806
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 23:02:33
What is LEVCROMAKALIM?
The Uses of LEVCROMAKALIM
Levcromakalim is a potassium channel activator and vasorelaxant used in the management of hypertension in diabetes mellitus.
The Uses of LEVCROMAKALIM
Anti-asthmatic; antihypertensive.
What are the applications of Application
Levcromakalim is an active enantiomer of the prototypical KATP(Kir6) channel opener cromakalim
Definition
ChEBI: Levcromakalim is a 1-benzopyran.
Biological Activity
Active enantiomer of the prototypical K ATP channel opener cromakalim (trans-3,4-dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile ). Hypotensive and airways relaxant. IC 50 = 490 nM in guinea pig trachea.
storage
Store at RT
Properties of LEVCROMAKALIM
| Melting point: | 242-244° |
| Boiling point: | 482.3±45.0 °C(Predicted) |
| alpha | D26 -52.2° (c = 1 in chloroform) |
| Density | 1.31±0.1 g/cm3(Predicted) |
| storage temp. | Store at RT |
| solubility | DMSO: ≤10 mM, soluble |
| form | solid |
| pka | 13.18±0.60(Predicted) |
| color | White to off-white |
Safety information for LEVCROMAKALIM
Computed Descriptors for LEVCROMAKALIM
New Products
4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Mefenamic Acid IP/BP/EP/USP Diclofenac Sodium IP/BP/EP/USP Ornidazole IP Diclofenac Potassium SODIUM AAS SOLUTION ZINC AAS SOLUTION BUFFER SOLUTION PH 10.0(BORATE) GOOCH CRUCIBLE SINTERED AQUANIL 5 BERYLLIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
![4-[3-(Dimethylamino)propoxy]benzonitrile](https://img.chemicalbook.in/CAS/GIF/146440-15-5.gif)
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