LEUROSINE
- CAS NO.：23360-92-1
- Empirical Formula: C46H56N4O9
- Molecular Weight: 808.97
- MDL number: MFCD01716248
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-20 13:16:41
What is LEUROSINE?
Description
Vinqa rosea yields this complex dimeric alkaloid which forms colourless crystals that are best purified by recrystallization from acetonitrile. It crystallizes with 8 moles of H20 and loses solvent when heated at In-5°C. It is also dextro? rotatory with [α]26D + n° (CHCI3)’ A crystalline SUlphate is known which has m.p. 238-242°C (dec.) and [α]D - 8.3° (MeOH). The N(b)-oxide is identical with pleurosine (q.v.).
The Uses of LEUROSINE
Antineoplastic.
The Uses of LEUROSINE
Vinleurosine is an antitumor compound derived from Vinca Rosea.
Definition
ChEBI: Leurosine is a vinca alkaloid.
References
Svoboda., J. Amer. Pharm. Assoc., 47,834 (1959)
Neuss et al., J. Amer. Chern. Soc., 81,4754 (1959)
Revised structure:
Neuss et al., Tetrahedron Lett., 783 (1968)
Properties of LEUROSINE
| Melting point: | 202-205℃ |
| Density | 1.39 |
| pka | 11.36±0.60(Predicted) |
Safety information for LEUROSINE
Computed Descriptors for LEUROSINE
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![3-[(3-methoxyphenyl)amino]propanoic acid](https://img.chemicalbook.in/CAS/GIF/3334-67-6.gif)
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