LEUROSINE
- CAS NO.:23360-92-1
- Empirical Formula: C46H56N4O9
- Molecular Weight: 808.97
- MDL number: MFCD01716248
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:36
What is LEUROSINE?
Description
Vinqa rosea yields this complex dimeric alkaloid which forms colourless crystals that are best purified by recrystallization from acetonitrile. It crystallizes with 8 moles of H20 and loses solvent when heated at In-5°C. It is also dextro? rotatory with [α]26D + n° (CHCI3)’ A crystalline SUlphate is known which has m.p. 238-242°C (dec.) and [α]D - 8.3° (MeOH). The N(b)-oxide is identical with pleurosine (q.v.).
The Uses of LEUROSINE
Vinleurosine is an antitumor compound derived from Vinca Rosea.
The Uses of LEUROSINE
Antineoplastic.
Definition
ChEBI: Leurosine is a vinca alkaloid.
References
Svoboda., J. Amer. Pharm. Assoc., 47,834 (1959)
Neuss et al., J. Amer. Chern. Soc., 81,4754 (1959)
Revised structure:
Neuss et al., Tetrahedron Lett., 783 (1968)
Properties of LEUROSINE
Melting point: | 202-205℃ |
Density | 1.39 |
pka | 11.36±0.60(Predicted) |
Safety information for LEUROSINE
Computed Descriptors for LEUROSINE
Related products of tetrahydrofuran
VincristineM1
4'-Deoxy Vincristine
N-Desmethylvinblastine
3-AMINO-4-ETHYL-OCTANOIC ACID
1-(2-(2-Methyl-1H-indol-3-yl)ethyl)-3-piperidinol
(2R,3R)-3-AMINO-2-HYDROXYHEXANOIC ACID
(2S,3R)-3-AMINO-2-HYDROXY-4-PHENYLBUTYRIC ACID HYDROCHLORIDE
3-[(3-methoxyphenyl)amino]propanoic acid
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