[LEU5]-ENKEPHALIN

CAS NO.：58822-25-6
Empirical Formula: C28H37N5O7
Molecular Weight: 555.62
MDL number: MFCD00076406
EINECS: 261-457-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-07-02 08:55:42

What is [LEU5]-ENKEPHALIN?

The Uses of [LEU5]-ENKEPHALIN

Endogenous opioid neurotransmitter/neuromodulator that is an agonist at ? and δ opioid receptors, localization in brain parallels the localization of δ receptors.

What are the applications of Application

Leu-Enkephalin is an endogenous agonist for the receptors that are stimulated by opiate alkaloids

Definition

ChEBI: Leu-enkephalin is a pentapeptide comprising L-tyrosine, glycine, glycine, L-phenylalanine and L-leucine residues joined in sequence by peptide linkages. It is an endogenous opioid peptide produced in vertebrate species, including rodents, primates and humans that results from decomposition of proenkephalin or dynorphin and exhibits antinociceptive properties. It has a role as a delta-opioid receptor agonist, a mu-opioid receptor agonist, a neurotransmitter, an analgesic, a human metabolite and a rat metabolite. It is functionally related to a L-tyrosine, a glycine, a L-phenylalanine and a L-leucine. It is a tautomer of a Leu-enkephalin zwitterion.

storage

Store at -20°C

Properties of [LEU5]-ENKEPHALIN

Melting point:	130-133 °C
alpha	+32.3°(c=9,メタノール)
Boiling point:	998.8±65.0 °C(Predicted)
Density	1.274±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility	≥54.6 mg/mL in H2O; ≥54.8 mg/mL in EtOH; ≥55.6 mg/mL in DMSO
pka	3.40±0.10(Predicted)
form	Lyophilized powder
color	White to light yellow
Water Solubility	Soluble in water (1 mg/ml ).