[LEU5]-ENKEPHALIN
- CAS NO.:58822-25-6
- Empirical Formula: C28H37N5O7
- Molecular Weight: 555.62
- MDL number: MFCD00076406
- EINECS: 261-457-1
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-31 20:01:59
What is [LEU5]-ENKEPHALIN?
The Uses of [LEU5]-ENKEPHALIN
Endogenous opioid neurotransmitter/neuromodulator that is an agonist at ? and δ opioid receptors, localization in brain parallels the localization of δ receptors.
What are the applications of Application
Leu-Enkephalin is an endogenous agonist for the receptors that are stimulated by opiate alkaloids
Definition
ChEBI: Leu-enkephalin is a pentapeptide comprising L-tyrosine, glycine, glycine, L-phenylalanine and L-leucine residues joined in sequence by peptide linkages. It is an endogenous opioid peptide produced in vertebrate species, including rodents, primates and humans that results from decomposition of proenkephalin or dynorphin and exhibits antinociceptive properties. It has a role as a delta-opioid receptor agonist, a mu-opioid receptor agonist, a neurotransmitter, an analgesic, a human metabolite and a rat metabolite. It is functionally related to a L-tyrosine, a glycine, a L-phenylalanine and a L-leucine. It is a tautomer of a Leu-enkephalin zwitterion.
storage
Store at -20°C
Properties of [LEU5]-ENKEPHALIN
Melting point: | 130-133 °C |
alpha | +32.3°(c=9,メタノール) |
Boiling point: | 998.8±65.0 °C(Predicted) |
Density | 1.274±0.06 g/cm3(Predicted) |
storage temp. | Keep in dark place,Sealed in dry,Store in freezer, under -20°C |
solubility | ≥54.6 mg/mL in H2O; ≥54.8 mg/mL in EtOH; ≥55.6 mg/mL in DMSO |
pka | 3.40±0.10(Predicted) |
form | Lyophilized powder |
color | White to light yellow |
Water Solubility | Soluble in water (1 mg/ml ). |
Safety information for [LEU5]-ENKEPHALIN
Computed Descriptors for [LEU5]-ENKEPHALIN
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