Lercanidipine hydrochloride
Synonym(s):1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester 3,5-pyridinedicarboxylic acid hydrochloride
- CAS NO.:132866-11-6
- Empirical Formula: C36H42ClN3O6
- Molecular Weight: 648.19
- MDL number: MFCD07773089
- EINECS: 603-682-3
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-09 19:38:33
What is Lercanidipine hydrochloride?
Chemical properties
Pale-Yellow Powder
The Uses of Lercanidipine hydrochloride
A dihydropyridine calcium channel blocker. Antihypertensive.
The Uses of Lercanidipine hydrochloride
long-acting dihydropyridine calcium channel blocker, antihypertensive
What are the applications of Application
Lercanidipine hydrochloride hemihydrate is a Ca inhibitor
What are the applications of Application
Lercanidipine hydrochloride is a calcium channel protein inhibitor
Definition
ChEBI: Lercanidipine hydrochloride is a diarylmethane.
brand name
Cardiovasc (Recor dati, Italy); Carmen (Recordati, Italy); Corifeo (Recordati, Italy); Lercadip (Recordati, Italy); Lercan (Recordati, Italy); Lercapin (Recordati, Italy); Lercaton (Recordati, Italy); Lerkamen (Recordati, Italy); Lerzam (Recordati, Italy); Renovia (Recordati, Italy); Vasodip (Recordati, Italy); Zandip (Recordati, Italy); Zanicor (Recordati, Italy).
Biological Activity
L-type Ca 2+ channel blocker that displays higher vascular selectivity than Felodipine (4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester ). Causes peripheral vasodilation with only weak negative inotropic activity. Antihypertensive.
Biochem/physiol Actions
Lercanidipine hydrochloride is a L-type (Cav1.2b) vascular channel antagonist; L-type (Cav1.2a) cardiac channel agonist voltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine.
Properties of Lercanidipine hydrochloride
Melting point: | 175-177°C |
storage temp. | 2-8°C |
solubility | soluble in Methanol |
form | powder |
color | yellow |
Merck | 14,5446 |
CAS DataBase Reference | 132866-11-6(CAS DataBase Reference) |
Safety information for Lercanidipine hydrochloride
Signal word | Danger |
Pictogram(s) |
Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H301:Acute toxicity,oral |
Precautionary Statement Codes |
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for Lercanidipine hydrochloride
InChIKey | WMFYOYKPJLRMJI-UHFFFAOYSA-N |
Abamectin manufacturer
Hikal Ltd.
Sun Pharmaceutical Industries Ltd
Basil Drugs AND Pharmaceuticals Pvt Ltd
Ralington Pharma
Alfa Omega Pharma
Biophore India Pharmaceuticals Pvt Ltd
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