laudanosine
- CAS NO.:2688-77-9
- Empirical Formula: C21H27NO4
- Molecular Weight: 357.44
- MDL number: MFCD27978049
- EINECS: 220-253-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is laudanosine ?
The Uses of laudanosine
Laudanosine is a metabolite of the neuromuscular-blocking drugs Atracurium (A794500) and Cisatracurium (C496700) with potentially toxic systemic effects. It crosses the blood-brain barrier and may cause excitement and seizure activity.
Definition
ChEBI: Laudanosine is a member of isoquinolines.
Purification Methods
Crystallise these from EtOH. The (±)-picrate crystallises from EtOH with m 177-178o. The (-)-isomer has m 83-85o and
Properties of laudanosine
Melting point: | 89° |
Boiling point: | 490.07°C (rough estimate) |
alpha | D16 +106° (c = 1.6 in 97% alc); D16 +130° (chloroform); D22 +52.2 ±1.3° (chloroform); D20 +82.5° (ethanol) |
Density | 1.1729 (rough estimate) |
refractive index | 1.5614 (estimate) |
storage temp. | -20°C Freezer |
solubility | Chloroform (Slightly), Ethanol (Slightly), Methanol (Slightly, Sonicated) |
form | White to Pale Beige |
pka | 7.80±0.40(Predicted) |
Safety information for laudanosine
Computed Descriptors for laudanosine
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
Atracurium Impurity 19
Atracurium Impurity 15
Atracurium EP Impurity K Iodide (Mixture of Diastereomers)
Atracurium Impurity 27 Besylate
PHENYL P-TOLYL SULFONE
(R-trans, R-trans)-AtracuriuM Besylate
Atracurium Impurity 1
Atracurium EP Impurity D Iodide (Mixture of Diastereomers)
You may like
-
1-Methyl-6-oxo-1,6-dihydropyridazine-3-carbonitrile 98%View Details
99903-60-3 -
88491-46-7 98%View Details
88491-46-7 -
1823368-42-8 98%View Details
1823368-42-8 -
2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%View Details
1307449-08-6 -
Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%View Details
25408-95-1 -
2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%View Details
1805639-70-6 -
1784294-80-9 98%View Details
1784294-80-9 -
Lithium ClavulanateView Details
61177-44-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.