L-NORADRENALINE BITARTRATE
Synonym(s):L -(−)-Noradrenaline (+)-bitartrate salt monohydrate;L- (−)-Norepinephrine (+)-bitartrate salt monohydrate
- CAS NO.：51-40-1
- Empirical Formula: C8H11NO3.C4H6O6
- Molecular Weight: 319.26
- MDL number: MFCD00036384
- EINECS: 200-095-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-30 15:45:59
What is L-NORADRENALINE BITARTRATE?
The Uses of L-NORADRENALINE BITARTRATE
Adrenergic (vasoconstrictor).
brand name
Levophed (Hospira).
Clinical Use
Hypotension
Cardiac arrest (sympathomimetic)
Safety Profile
Poison by intravenous andintraperitoneal routes. When heated to decomposition itemits toxic fumes of NOx.
Drug interactions
Potentially hazardous interactions with other drugs
Adrenergic neurone blockers: antagonise hypotensive
effect.
Anaesthetics: increased risk of arrhythmias with
volatile general anaesthetics.
Antidepressants: tricyclics may cause hypertension
and arrhythmias; MAOIs and moclobemide may
cause hypertensive crisis.
Beta-blockers: can cause severe hypertension.
Clonidine: possibly increased risk of hypertension.
Dopaminergics: effects possibly increased by
entacapone; avoid with rasagiline.
Sympathomimetics: effects possibly enhanced by
dopexamine.
Metabolism
Extensively metabolised by catechol-O-methyltransferase
(COMT), and monoamine oxidase (MAO).
Up to 16% of an intravenous dose is excreted unchanged
in the urine with methylated and deaminated metabolites
in free and conjugated forms.
storage
Store at +4°C
Properties of L-NORADRENALINE BITARTRATE
| storage temp. | Store at 4°C, protect from light |
| solubility | 31.93mg/mL in DMSO |
| Melting point: | 102-104 °C |
| pka | 8.64(at 25℃) |
| Water Solubility | 31.93mg/mL in Water |
| CAS DataBase Reference | 51-40-1(CAS DataBase Reference) |
Safety information for L-NORADRENALINE BITARTRATE
Computed Descriptors for L-NORADRENALINE BITARTRATE
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