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HomeProduct name listL-Leucyl-L-Leucine methyl ester (hydrochloride)

L-Leucyl-L-Leucine methyl ester (hydrochloride)

  • CAS NO.：6491-83-4
  • Empirical Formula: C13H27ClN2O3
  • Molecular Weight: 294.81808
  • MDL number: MFCD00155477
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-20 11:41:24
L-Leucyl-L-Leucine methyl ester (hydrochloride) Structural

What is L-Leucyl-L-Leucine methyl ester (hydrochloride)?

Description

L-Leucyl-L-Leucine methyl ester (LLME) is a lysosomal condensation product that has been reported to be cytotoxic towards natural killer cells and CD4+ and CD8+ T lymphocytes without affecting helper T cells and B cells. It has also been shown to induce death of monocytes, polymorphonuclear leukocytes, and myeloid tumor cells. Upon entry into cells via receptor-mediated endocytosis, LLME undergoes a condensation process catalyzed by dipeptidyl peptidase I (DPPI) in lysosomes. This condensation leads to lysosomal rupture and DNA fragmentation in DPPI-expressing immune cells such as cytotoxic T cells and natural killer cells.

The Uses of L-Leucyl-L-Leucine methyl ester (hydrochloride)

H-Leu-leu-OMe HCl

What are the applications of Application

H-Leu-Leu-OMe Hydrochloride is an immunosuppressant for biological applications

Properties of L-Leucyl-L-Leucine methyl ester (hydrochloride)

Melting point: 177-181°C
storage temp.  Hygroscopic, Refrigerator, under inert atmosphere
solubility  DMSO (Slightly), Water (Slightly)
form  Solid
color  White to Off-White
Stability: Hygroscopic

Safety information for L-Leucyl-L-Leucine methyl ester (hydrochloride)

Computed Descriptors for L-Leucyl-L-Leucine methyl ester (hydrochloride)

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