L-4-Fluorophenylalanine
- CAS NO.:1132-68-9
- Empirical Formula: C9H10FNO2
- Molecular Weight: 183.18
- MDL number: MFCD00063064
- EINECS: 145-896-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is L-4-Fluorophenylalanine?
Chemical properties
white to off-white powder
The Uses of L-4-Fluorophenylalanine
4-Fluoro-L-phenylalanine is a substrate for tyrosine hydroxylase (TH) that has been used to study the regulation of that enzyme.
What are the applications of Application
L-4-Fluoro-phenyl-alanine is a TH substrate which appears to inhibit mitosis and arrest cells in G2
Definition
ChEBI: A L-phenylalanine derivative that is L-phenylalanine in which the hydrogen at position 4 on the benzene ring is replaced by a fluoro group.
Purification Methods
It is recrystallised from aqueous EtOH. The (R)-N-acetyl derivative has m 142-145o, [] D -38.6o (c 8, EtOH). [Bennett & Nieman J Am Chem Soc 72 1800 1950, Beilstein 14 III 1268.]
Properties of L-4-Fluorophenylalanine
Melting point: | ~255 °C (dec.) |
Boiling point: | 313.3±32.0 °C(Predicted) |
alpha | -26.5 º (c=1, H2O 25 ºC) |
Density | 1.1939 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
form | powder to crystal |
pka | 2.20±0.10(Predicted) |
color | White to Almost white |
Water Solubility | Soluble in water and 0.5M HCl (50 mg/ml). |
BRN | 2416148 |
CAS DataBase Reference | 1132-68-9(CAS DataBase Reference) |
Safety information for L-4-Fluorophenylalanine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H332:Acute toxicity,inhalation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for L-4-Fluorophenylalanine
L-4-Fluorophenylalanine manufacturer
JSK Chemicals
2Y
Phone:+919879767970
Whatsapp: +91 9879767970
product: 1132-68-9 4-Fluoro-L-phenylalanine,98% 99%
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
H-PHE-ALA-OH
PHE-GLY-GLY
4-Methylphenyl-L-alanine
H-4-NITRO-PHE-OET HCL
L-4-BENZOYLPHENYLALANINE
L-4-Iodophenylalanine
4-Methoxy-L-phenylalanine
L-4-Chlorophenylalanine
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