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HomeProduct name listKushenol K

Kushenol K

  • CAS NO.:101236-49-1
  • Empirical Formula: C26H32O8
  • Molecular Weight: 472.53
  • MDL number: MFCD31579630
  • Update Date: 2023-04-23 13:52:06
Kushenol K Structural

What is Kushenol K?

Biological Activity

Kushenol K, a flavonoid antioxidant from Sophora flavescens. It can inhibit the activity of SGLT1 and SGLT2 and used as an inhibitor of CYP3A4 with a Ki value of 1.35 μM.

in vivo

When Midazolam is used as the substrate of CYP3A4, Kushenol K exhibits the strong inhibition with an IC 50 values of 1.62 μM.
At a concentration of 50 μM, the The inhibition rate of Kushenol K on SGLT1 is 29.7%, and the inhibition rate on SGLT2 is 43.7%.

Properties of Kushenol K

solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form  Powder

Safety information for Kushenol K

Computed Descriptors for Kushenol K

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