KIGAMICIN C
- CAS NO.：680571-51-1
- Empirical Formula: C41H47NO16
- Molecular Weight: 809.81
- MDL number: MFCD09954098
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-21 10:59:17
What is KIGAMICIN C?
The Uses of KIGAMICIN C
Kigamicin C was discovered by an anti-austerity strategy, targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions. The mechanism of action is proposed to be via blockade of aPKB/Akt activation, caused by the withdrawal of nutrients. It is active in vivo against a human pancreatic cancer xenograft model. Kigamicin C also inhibits the growth of Gram positive bacteria including MRSA, but is not active against Gram negative bacteria.
The Uses of KIGAMICIN C
Kigamicin C is a novel antibiotic antiproliferative with novel action.
What are the applications of Application
Kigamicin C is a novel antibiotic antiproliferative with novel action
Properties of KIGAMICIN C
| storage temp. | Store at -20°C |
| solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble |
| form | Yellow powder. |
Safety information for KIGAMICIN C
Computed Descriptors for KIGAMICIN C
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