KIGAMICIN C
- CAS NO.:680571-51-1
- Empirical Formula: C41H47NO16
- Molecular Weight: 809.81
- MDL number: MFCD09954098
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-21 10:59:17
What is KIGAMICIN C?
The Uses of KIGAMICIN C
Kigamicin C was discovered by an anti-austerity strategy, targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions. The mechanism of action is proposed to be via blockade of aPKB/Akt activation, caused by the withdrawal of nutrients. It is active in vivo against a human pancreatic cancer xenograft model. Kigamicin C also inhibits the growth of Gram positive bacteria including MRSA, but is not active against Gram negative bacteria.
The Uses of KIGAMICIN C
Kigamicin C is a novel antibiotic antiproliferative with novel action.
What are the applications of Application
Kigamicin C is a novel antibiotic antiproliferative with novel action
Properties of KIGAMICIN C
storage temp. | Store at -20°C |
solubility | DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble |
form | Yellow powder. |
Safety information for KIGAMICIN C
Computed Descriptors for KIGAMICIN C
New Products
4-AMINO-TETRAHYDRO-PYRAN-4-CARBOXYLIC ACID HCL 4-(Dimethylamino)tetrahydro-2H-pyran-4-carbonitrile 4-Aminotetrahydropyran-4-carbonitrile Hydrochloride (R)-3-Aminobutanenitrile Hydrochloride 3-((Dimethylamino)methyl)-5-methylhexan-2-one oxalate 1,4-Dioxa-8-azaspiro[4.5]decane 5-Bromo-2-nitropyridine Nimesulide BP Aceclofenac IP/BP/EP Diclofenac Sodium IP/BP/EP/USP Mefenamic Acid IP/BP/EP/USP Ornidazole IP Diclofenac Potassium THOMAIND PAPER PH 2.0 TO 4.5 1 BOX BUFFER CAPSULE PH 9.2 - 10 CAP SODIUM CHLORIDE 0.1N CVS ALLOXAN MONOHYDRATE 98% PLATINUM 0.5% ON 3 MM ALUMINA PELLETS (TYPE 73) LITHIUM AAS SOLUTION 2-Bromo-1-(bromomethyl)-3-chloro-5-nitrobenzene 2-Bromo-3-nitroaniline N-(3-Hydroxypropyl)-N-methylacetamide 3-Bromo-6-chloropyridazine 4-ethyl-3-nitrobenzoic acidRelated products of tetrahydrofuran
6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 4-(6-deoxy-alpha-galactofuranosy l)-1-hydroxy-10,12-dimethoxy-8-methyl-
anguinomycin A
21-hydroxyoligomycin A
Cochliodinol,fromChaetomiumglobosum.
Hexacyclinic acid
Cladospirone bisepoxide
echinosporin
KAZUSAMYCIN A FROM STREPTOMYCES SP.
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