ISOVALERYL-L-CARNITINE CHLORIDE
- CAS NO.：139144-12-0
- Empirical Formula: C12H22ClNO3
- Molecular Weight: 263.76098
- MDL number: MFCD09263554
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:03:09
What is ISOVALERYL-L-CARNITINE CHLORIDE?
Description
Isovaleryl-L-carnitine is a naturally occurring acylcarnitine that is formed via metabolic conversion of L-leucine. It increases survival and decreases apoptosis in hepatocyte growth factor-deprived murine C2.8 hepatocytes when used at a concentration of 1 mM. Isovaleryl-L-carnitine inhibits amino acid deprivation-induced proteolysis and autophagy in isolated perfused rat liver when used at concentrations of 77 and 100 μM, respectively. Increased levels of isovaleryl carnitine are associated with isovaleryl-CoA dehydrogenase deficiency (isovaleric acidemia).
The Uses of ISOVALERYL-L-CARNITINE CHLORIDE
Isovaleryl L-Carnitine Chloride is used to prepare carnitine benzyl esters as neuroprotectant prodrugs.
Properties of ISOVALERYL-L-CARNITINE CHLORIDE
| Melting point: | >160°C (dec.) |
| storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere |
| solubility | Methanol (Slightly), Water (Slightly, Heated) |
| form | Solid |
| color | White to Off-White |
| Stability: | Hygroscopic |
Safety information for ISOVALERYL-L-CARNITINE CHLORIDE
Computed Descriptors for ISOVALERYL-L-CARNITINE CHLORIDE
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