Isopropyl chloroacetate
- CAS NO.:105-48-6
- Empirical Formula: C5H9ClO2
- Molecular Weight: 136.58
- MDL number: MFCD00040410
- EINECS: 203-301-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:30
What is Isopropyl chloroacetate?
Chemical properties
CLEAR COLOURLESS TO ALMOST COLOURLESS LIQUID
The Uses of Isopropyl chloroacetate
Isopropyl Chloroacetate is used as a reactant in the design, synthesis, and 3D-QSAR analysis of novel oxadiazolones as protoporphyrinogen oxidase inhibitors.
General Description
A clear colorless liquid. Flash point near 60°F. Boiling point near 200°F. Less dense than water. Vapors heavier than air. Used to make other chemicals.
Air & Water Reactions
Highly flammable. Soluble in water.
Reactivity Profile
Isopropyl chloroacetate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.
Health Hazard
TOXIC; inhalation, ingestion or contact (skin, eyes) with vapors, dusts or substance may cause severe injury, burns or death. Bromoacetates and chloroacetates are extremely irritating/lachrymators. Reaction with water or moist air will release toxic, corrosive or flammable gases. Reaction with water may generate much heat that will increase the concentration of fumes in the air. Fire will produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapors may travel to source of ignition and flash back. Substance will react with water (some violently) releasing flammable, toxic or corrosive gases and runoff. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated or if contaminated with water.
Properties of Isopropyl chloroacetate
Boiling point: | 149-150 °C(lit.) |
Density | 1.096 g/mL at 25 °C(lit.) |
refractive index | n |
Flash point: | 159 °F |
form | clear liquid |
color | Colorless to Almost colorless |
Water Solubility | SLIGHTLY SOLUBLE |
CAS DataBase Reference | 105-48-6(CAS DataBase Reference) |
NIST Chemistry Reference | Chloroacetic acid isopropyl ester(105-48-6) |
EPA Substance Registry System | Acetic acid, chloro-, 1-methylethyl ester (105-48-6) |
Safety information for Isopropyl chloroacetate
Signal word | Danger |
Pictogram(s) |
Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H226:Flammable liquids H301:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P370+P378:In case of fire: Use … for extinction. P405:Store locked up. P403+P233:Store in a well-ventilated place. Keep container tightly closed. P501:Dispose of contents/container to..… |
Computed Descriptors for Isopropyl chloroacetate
Isopropyl chloroacetate manufacturer
Manik Laboratories
JSK Chemicals
Supra Group of Companies
Sontara Organo Industries
Sunmoon Pharmaceuticals Pvt Ltd
Anand Agencies
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