isometheptene
- CAS NO.：503-01-5
- Empirical Formula: C9H19N
- Molecular Weight: 141.256
- MDL number: MFCD00273385
- EINECS: 207-959-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:30
What is isometheptene?
Originator
Octinum,Knoll,US,1948
The Uses of isometheptene
ctin (Knoll).
The Uses of isometheptene
6-Methylamino-2-methylheptene is an intermediate for the synthesis of Isometheptene Maleate (I821325), which belongs to a group of sympathomimetic amine and shows very little antihypertensive activity. Isometheptene Maleate is used as an antispasmodic drug.
Indications
Isometheptene is a sympathomimetic drug which causes vasoconstriction. It is used for treating migraines and tension headaches.
Background
Isometheptene is a sympathomimetic drug that causes vasoconstriction. It is used for treating migraines and tension headaches.
Definition
ChEBI: Isometheptene is a secondary amino compound.
Manufacturing Process
Methyl heptenone dissolved in 75% alcohol is reduced with activated aluminum in the presence of methylamine to give isometheptene.
Therapeutic Function
Muscle relaxant
Pharmacokinetics
Isometheptene Mucate is an indirect-acting sympathomimetic. Due to its vasoconstricting properties, Isometheptene Mucate is used for the treatment of acute migraine attacks, usually in combination with other analgeics. It can also displace catecholamines from vesicles inside the neuron leading to the sympathetic responses it is known for.
Metabolism
Not Available
Properties of isometheptene
| Boiling point: | bp 176-178°; bp7 58-59° |
| Density | 0.795 |
| vapor pressure | 1.39hPa at 25℃ |
| refractive index | nD15 1.4472 |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 10.78±0.10(Predicted) |
| form | Oil |
| color | Colourless to Pale Yellow |
| Water Solubility | 3.06g/L at 25℃ |
| EPA Substance Registry System | 5-Hepten-2-amine, N,6-dimethyl- (503-01-5) |
Safety information for isometheptene
Computed Descriptors for isometheptene
New Products
4-Fluorophenylacetic acid 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate (6-METHYL-[1,3]DITHIOLO[4,5-b]QUINOXALIN-2-ONE INDAZOLE-3-CARBOXYLIC ACID 4-IODO BENZOIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5,6-Dimethoxyindanone 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
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