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Isoliensinine

Isoliensinine Structural

What is Isoliensinine?

Description

Tomita and his co-workers have obtained this bisisoquinoline alkaloid from the embryo of the seeds of Nelumbo nucifera Gaertn. The base has [α]29D + 49.3° (Me2CO) and - 43.3° (CHC13 ). The hydrochloride tetrahydrate forms colourless crystals, m.p. l85-6°C (dry); the perchlorate monohydrate has m.p. 200-3°C (dry); [α]22D - 70° (Me2CO) and the styphnate of the O,O-dimethyl ether, also crystalline, has m.p. l33-5°C; [α]27D - 81.5° (Me2CO). Three methoxyl, two hydroxyl and two methylimino groups are present.

The Uses of Isoliensinine

(+)-Isoliensinine is an alkaloid which displays activation of AMP-activated kinase and regulation of PPARγ receptors.

Definition

ChEBI: Isoliensinine is a member of isoquinolines.

References

Tomita et aI., Tetrahedron Lett., 2637,3374 (1964)

Properties of Isoliensinine

Melting point: 69-71℃
Boiling point: 723.1±60.0 °C(Predicted)
Density  1.218
storage temp.  2-8°C(protect from light)
solubility  Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form  powder
pka 9.28±0.45(Predicted)
color  White

Safety information for Isoliensinine

Computed Descriptors for Isoliensinine

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