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HomeProduct name listIsoacteoside

Isoacteoside

Synonym(s):(E)-2-(3,4-dihydroxyphenyl)ethyl 3-O-(6-deoxy-α-L-mannopyranosyl)-, 6-(3-(3,4-dihydroxyphenyl)-β-D-glucopyranoside;Isoacteoside;Isoverbascoside

Isoacteoside Structural

What is Isoacteoside?

Description

Isoverbascoside is a phenylethanoid glycoside that has been found in C. trichotomum and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; ) radicals in a cell-free assay and inhibits hydrogen peroxide-induced lipid peroxidation in V79-4 cells when used at a concentration of 10 μg/ml. Isoverbascoside (7.5-30 μM) induces apoptosis and production of reactive oxygen species (ROS) in, and reduces viability of, OVCAR-3 cells. It inhibits tumor growth in an OVCAR-3 mouse xenograft model when administered at a dose of 30 mg/kg. Isoverbascoside (2.5 and 5 mg/kg) decreases brain amyloid deposition and increases exploratory behavior in rats when infused into the cerebral ventricles with amyloid-β (1-42) (Aβ42; ). It also decreases xylene-induced ear edema in mice and increases survival in a mouse model of LPS-induced endotoxic shock.

The Uses of Isoacteoside

Isoacteoside is a possible food antioxidant.

What are the applications of Application

Isoacteoside is a glycoside

Definition

ChEBI: Isoacteoside is a hydroxycinnamic acid.

Properties of Isoacteoside

Melting point: 220~230℃
Boiling point: 942.9±65.0 °C(Predicted)
Density  1.60±0.1 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  DMSO : ≥ 48 mg/mL (76.85 mM)
form  Powder
pka 9.32±0.10(Predicted)
color  White to yellow

Safety information for Isoacteoside

Computed Descriptors for Isoacteoside

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