H-GLY-TYR-PRO-GLY-GLN-VAL-OH
Synonym(s):Glycyl-L-tyrosyl-L-prolyl-glycyl-L-glutaminyl-L-valine trifluoroacetate salt;Gly-Tyr-Pro-Gly-Gln-Val trifluoroacetate salt;PAR 4 (1-6)
- CAS NO.:225779-44-2
- Empirical Formula: C28H41N7O9
- Molecular Weight: 619.67
- MDL number: MFCD02181012
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is H-GLY-TYR-PRO-GLY-GLN-VAL-OH?
Description
PAR4 (1-6) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR4 and residues 48-53 of the full-length sequence. It activates PAR4 and the cleavage site mutant PAR4R47A when used at a concentration of 500 μM. PAR4 (1-6) induces platelet aggregation of isolated washed human platelets when used at a concentration of 1 mM but does not affect clotting time induced by factor VIIa, soluble tissue factor, and collagen in an ex vivo coagulation assay.
Properties of H-GLY-TYR-PRO-GLY-GLN-VAL-OH
storage temp. | -15°C
|
solubility | H2O: >2mg/mL |
form | powder |
color | white to tan |
Safety information for H-GLY-TYR-PRO-GLY-GLN-VAL-OH
Computed Descriptors for H-GLY-TYR-PRO-GLY-GLN-VAL-OH
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
VKGILS-NH2
H-GLY-TYR-PRO-GLY-LYS-PHE-NH2
H-SER-LEU-ILE-GLY-ARG-LEU-OH
(PHE1,SER2,TYR6)-PAR-1 (1-6) AMIDE (HUMAN)
COAGULATION FACTOR II RECEPTOR-LIKE 2 (1-6) AMIDE (MOUSE)
COAGULATION FACTOR II RECEPTOR-LIKE 2 (1-6) AMIDE (HUMAN)
H-SER-LEU-ILE-GLY-ARG-LEU-NH2
PAR-4 (1-6) amide (human)
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