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HomeProduct name listH-GLY-TYR-PRO-GLY-GLN-VAL-OH

H-GLY-TYR-PRO-GLY-GLN-VAL-OH

Synonym(s):Glycyl-L-tyrosyl-L-prolyl-glycyl-L-glutaminyl-L-valine trifluoroacetate salt;Gly-Tyr-Pro-Gly-Gln-Val trifluoroacetate salt;PAR 4 (1-6)

H-GLY-TYR-PRO-GLY-GLN-VAL-OH Structural

What is H-GLY-TYR-PRO-GLY-GLN-VAL-OH?

Description

PAR4 (1-6) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR4 and residues 48-53 of the full-length sequence. It activates PAR4 and the cleavage site mutant PAR4R47A when used at a concentration of 500 μM. PAR4 (1-6) induces platelet aggregation of isolated washed human platelets when used at a concentration of 1 mM but does not affect clotting time induced by factor VIIa, soluble tissue factor, and collagen in an ex vivo coagulation assay.

Properties of H-GLY-TYR-PRO-GLY-GLN-VAL-OH

storage temp.  -15°C
solubility  H2O: >2mg/mL
form  powder
color  white to tan

Safety information for H-GLY-TYR-PRO-GLY-GLN-VAL-OH

Computed Descriptors for H-GLY-TYR-PRO-GLY-GLN-VAL-OH

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