GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE
Synonym(s):cGMP;cyclic GMP
- CAS NO.：7665-99-8
- Empirical Formula: C10H12N5O7P
- Molecular Weight: 345.21
- MDL number: MFCD00070129
- EINECS: 231-641-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-02-06 18:17:50
What is GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE?
Chemical properties
White powder
The Uses of GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE
Guanosine 3'',5''-Cyclic Monophosphate is an intracellular second messenger which are involved in the transduction of a diverse array of stimuli, mediating metabolic and growth regulation.
What are the applications of Application
Guanosine 3′,5′-cyclic monophosphate is an important second messenger
Definition
ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP.
Biochem/physiol Actions
An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).
Properties of GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE
| Melting point: | >242°C (dec.) |
| Density | 2?+-.0.1 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | 1% sodium bicarbonate: 50 mg/mL |
| form | powder |
| pka | 1.03±0.60(Predicted) |
| color | white |
| Stability: | Hygroscopic |
Safety information for GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE
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