GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE

Synonym(s):cGMP;cyclic GMP

CAS NO.：7665-99-8
Empirical Formula: C10H12N5O7P
Molecular Weight: 345.21
MDL number: MFCD00070129
EINECS: 231-641-6
SAFETY DATA SHEET (SDS)
Update Date: 2024-02-06 18:17:50

GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE Structural

What is GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE?

Chemical properties

White powder

The Uses of GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE

Guanosine 3'',5''-Cyclic Monophosphate is an intracellular second messenger which are involved in the transduction of a diverse array of stimuli, mediating metabolic and growth regulation.

What are the applications of Application

Guanosine 3′,5′-cyclic monophosphate is an important second messenger

Definition

ChEBI: A 3',5'-cyclic purine nucleotide that is 3',5'-cyclic GMP.

Biochem/physiol Actions

An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).

Properties of GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE

Melting point:	>242°C (dec.)
Density	2?+-.0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	1% sodium bicarbonate: 50 mg/mL
form	powder
pka	1.03±0.60(Predicted)
color	white
Stability:	Hygroscopic

Safety information for GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.