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HomeProduct name listGMBS

GMBS

Synonym(s):N-(γ-Maleimidobutyryloxy)succinimide;N-Succinimidyl 4-maleimidobutyrate;4-Maleimidobutyric acid N-succinimidyl ester;GMBS;N-γ-Maleimidobutyryloxysuccinimide

  • CAS NO.:80307-12-6
  • Empirical Formula: C12H12N2O6
  • Molecular Weight: 280.23
  • MDL number: MFCD00036817
  • EINECS: 625-693-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-28 23:16:16
GMBS Structural

What is GMBS?

Chemical properties

White Solid

The Uses of GMBS

A short, sulfhydryl and amino reactive heterobifunctional crosslinking reagent. Introduces maleimide groups into IgM

The Uses of GMBS

A heterobifunctional cross-linking reagent with amine and sulfhydryl reactivity. Useful in enzyme immunoassays

What are the applications of Application

4-Maleimidobutyric Acid N-Succinimidyl Ester is An amine- and sulfhydryl-reactive crosslinker

Properties of GMBS

Melting point: 123-129 °C
Boiling point: 461.3±47.0 °C(Predicted)
Density  1.49±0.1 g/cm3(Predicted)
storage temp.  2-8°C
solubility  chloroform: 100 mg/mL
pka -2.27±0.20(Predicted)
form  powder
color  White to Pale Yellow
BRN  6427689
Stability: Hygroscopic, Moisture Sensitive
InChI InChI=1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2

Safety information for GMBS

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for GMBS

InChIKey PVGATNRYUYNBHO-UHFFFAOYSA-N
SMILES N1(CCCC(ON2C(=O)CCC2=O)=O)C(=O)C=CC1=O

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