GGTI-2133

Synonym(s):N-[[4-(Imidazol-4-yl)methylamino]-2-(1-naphthyl)benzoyl]leucine trifluoroacetate salt

Empirical Formula: C27H26N4O3
Molecular Weight: 454.52
MDL number: MFCD02683592
Update Date: 2023-04-23 13:52:06

What is GGTI-2133?

The Uses of GGTI-2133

GGTI-2133 i an inhibitors of protein geranylgeranyltransferase-I. Increases prelamin A accumulation by inhibiting ZMPSTE24 protein in human fibroblast. GGTI-2133 inhibited proliferation and migration via involvement of RhoA and RalB proteins in human oral squamous cell carcinoma cell.

Properties of GGTI-2133

Melting point:	103-118.5 °C
storage temp.	-20°C
form	solid
color	white to beige

Safety information for GGTI-2133

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for GGTI-2133

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