Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listGDF-8

GDF-8

Synonym(s):GDF8;Growth/differentiation factor 8;MSTN;Myostatin

  • Molecular Weight: 0
  • MDL number: MFCD03457656
  • EINECS: 200-001-8
  • Update Date: 2024-07-03 11:31:34

What is GDF-8?

Description

Myostatin (GDF-8), a member of the TGF-beta superfamily of growth and differentiation factors, is most well-known as a potent suppressor of muscle growth, development, and regeneration. It is highly expressed in skeletal muscle, and myostatin loss-of-function leads to doubling skeletal muscle mass. Mice lacking myostatin show a significant increase in muscle mass, and congenital absence of myostatin is associated with increased muscle mass in humans and dogs. It has also been shown that factors which inhibit myostatin, such as follistatin, can improve muscle regeneration and decrease fibrosis in injured muscles[1].

References

[1] Mark W Hamrick. “Recombinant myostatin (GDF-8) propeptide enhances the repair and regeneration of both muscle and bone in a model of deep penetrant musculoskeletal injury.” Journal of Trauma-Injury Infection and Critical Care 69 3 (2010): 579–83.

Properties of GDF-8

storage temp.  -20°C

Safety information for GDF-8

Computed Descriptors for GDF-8

You may like

  • Myostatin Proform human CAS
    Myostatin Proform human CAS
    View Details
  • Monoclonal Anti-MSTN antibody produced in mouse CAS
    Monoclonal Anti-MSTN antibody produced in mouse CAS
    View Details
  • Dimethyl [2-oxo-3-[3-(trifluoromethyl)phenoxy]propyl]phosphonate 99%
    Dimethyl [2-oxo-3-[3-(trifluoromethyl)phenoxy]propyl]phosphonate 99%
    54094-19-8
    View Details
  • 85-81-4 99%
    85-81-4 99%
    85-81-4
    View Details
  • 208111-98-2 (3aR,4R,5R,6aS)-5-(Benzoyloxy)hexahydro-4-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten- 1-yl]-2H-cyclopenta[b]furan-2-one 99%
    208111-98-2 (3aR,4R,5R,6aS)-5-(Benzoyloxy)hexahydro-4-[(1E)-3-oxo-4-[3-(trifluoromethyl)phenoxy]-1-buten- 1-yl]-2H-cyclopenta[b]furan-2-one 99%
    208111-98-2
    View Details
  • 2033-24-1 99%
    2033-24-1 99%
    2033-24-1
    View Details
  • Meldrums acid 2033-24-1 99%
    Meldrums acid 2033-24-1 99%
    2033-24-1
    View Details
  • 2-Aminopyridine 504-29-0 99%
    2-Aminopyridine 504-29-0 99%
    504-29-0
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.