GARCINOLIC ACID; TRANS-(SH)
- CAS NO.：91893-83-3
- Empirical Formula: C27H38O4
- Molecular Weight: 426.59
- Update Date: 2024-10-28 16:48:35
What is GARCINOLIC ACID; TRANS-(SH)?
Description
Garcinoic acid is a derivative of vitamin E originally isolated from C. grandiflora. It inhibits IL-1β-induced microsomal prostaglandin E2 synthase-1 (mPGES-1) activity in A549 cells when used at concentrations of 1 and 10 μM. It has higher antioxidant activity relative to (±)-α-tocopherol in a cell-free assay when used at a concentration of 0.15 mM.
The Uses of GARCINOLIC ACID; TRANS-(SH)
Garcinoic Acid displays anti-angiogenic activity as well as anti-oxidative activity in animals.
General Description
Natural product derived from plant source.
Properties of GARCINOLIC ACID; TRANS-(SH)
| Boiling point: | 602.6±55.0 °C(Predicted) |
| Density | 1.055±0.06 g/cm3(Predicted) |
| storage temp. | -20°C |
| solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:3): 0.25 mg/ml; Ethanol: 30 mg/ml |
| form | A film |
| pka | 5.00±0.19(Predicted) |
Safety information for GARCINOLIC ACID; TRANS-(SH)
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Environment GHS09 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. |
Computed Descriptors for GARCINOLIC ACID; TRANS-(SH)
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