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HomeProduct name listgamma-Benzyl L-glutamate

gamma-Benzyl L-glutamate

Synonym(s):L-Glutamic acid 5-benzyl ester

  • CAS NO.:1676-73-9
  • Empirical Formula: C12H15NO4
  • Molecular Weight: 237.25
  • MDL number: MFCD00002633
  • EINECS: 216-826-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-29 17:54:30
gamma-Benzyl L-glutamate Structural

What is gamma-Benzyl L-glutamate?

Chemical properties

white powder

The Uses of gamma-Benzyl L-glutamate

L-Glutamic acid γ-benzyl ester is commonly used in the synthesis of polymers for biological applications. Some of the examples are:

  • Synthesis of bioreducible block copolymers based on poly(ethylene glycol) and poly(γ-benzyl L-glutamate) for Intracellular drug delivery.
  • Synthesis of biodegradable poly(L-glutamic acid)-b-polylactide for magnetic resonance imaging (MRI)-visible drug delivery system.
  • Synthesis of pH and temperature-responsive diblock copolymers based on poly(L-glutamic acid).

Purification Methods

Recrystallise the ester from H2O and store it at 0o. [Estrin Biochemical Preparations 13 25 1971, Beilstein 6 IV 2538.]

Properties of gamma-Benzyl L-glutamate

Melting point: 181-182 °C(lit.)
Boiling point: 379.78°C (rough estimate)
alpha  27.2 º (c=2, 1N HCL)
Density  1.2026 (rough estimate)
refractive index  1.5200 (estimate)
storage temp.  2-8°C
solubility  Acetic Acid (Slightly), DMSO (Slightly, Heated), Methanol (Slightly, Heated)
form  Powder
pka 2.20±0.10(Predicted)
color  White
optical activity [α]20/D +19±2°, c = 1% in acetic acid
BRN  1885646
CAS DataBase Reference 1676-73-9(CAS DataBase Reference)
EPA Substance Registry System L-Glutamic acid, 5-(phenylmethyl) ester (1676-73-9)

Safety information for gamma-Benzyl L-glutamate

Computed Descriptors for gamma-Benzyl L-glutamate

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