FTY720-d4 Hydrochloride
- CAS NO.:1346604-90-7
- Empirical Formula: C19H34ClNO2
- Molecular Weight: 343.93176
- MDL number: MFCD32858129
- Update Date: 2024-10-28 23:16:16
What is FTY720-d4 Hydrochloride?
Chemical properties
White Solid
The Uses of FTY720-d4 Hydrochloride
A labelled derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. t is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
The Uses of FTY720-d4 Hydrochloride
A labelled derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).
Properties of FTY720-d4 Hydrochloride
Melting point: | 105-107°C |
storage temp. | Refrigerator |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
color | White |
Safety information for FTY720-d4 Hydrochloride
Computed Descriptors for FTY720-d4 Hydrochloride
New Products
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