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HomeProduct name listFTY720-d4 Hydrochloride

FTY720-d4 Hydrochloride

  • CAS NO.:1346604-90-7
  • Empirical Formula: C19H34ClNO2
  • Molecular Weight: 343.93176
  • MDL number: MFCD32858129
  • Update Date: 2024-10-28 23:16:16
FTY720-d4 Hydrochloride Structural

What is FTY720-d4 Hydrochloride?

Chemical properties

White Solid

The Uses of FTY720-d4 Hydrochloride

A labelled derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. t is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).

The Uses of FTY720-d4 Hydrochloride

A labelled derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analogue of Sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numberour models by inhibiting lymphocyte emigration from lymphoid organs. Reported to be phosphorylated by sphingosine kinase to FTY720-P, which has been shown to potently stimulate GTPgS binding activity in S1P-transfected CHO cells (EC50 = 210 pM, 4.9 nM, 4.3 nM, and 1 nM for S1P1, S1P3, S1P4 and S1P5, respectively).

Properties of FTY720-d4 Hydrochloride

Melting point: 105-107°C
storage temp.  Refrigerator
solubility  DMSO (Slightly), Methanol (Slightly)
form  Solid
color  White

Safety information for FTY720-d4 Hydrochloride

Computed Descriptors for FTY720-d4 Hydrochloride

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