Fmoc-N-amido-PEG24-acid
- CAS NO.：2170484-59-8
- Empirical Formula: C66H113NO28
- Molecular Weight: 1368.59
- MDL number: MFCD11041159
- Update Date: 2024-10-28 23:16:16
What is Fmoc-N-amido-PEG24-acid?
Description
Fmoc-N-amido-PEG24-acid contains an Fmoc-protected amine and a terminal carboxylic acid. The PEG spacer increases the aqueous solubility of the resulting compound. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid readily reacts with primary and secondary amine under EDC, DCC, HATU or other amide coupling conditions to form a stable amide bond.
Properties of Fmoc-N-amido-PEG24-acid
| Boiling point: | 1108.7±65.0 °C(Predicted) |
| Density | 1.152±0.06 g/cm3(Predicted) |
| pka | 4.28±0.10(Predicted) |
| color | White |
Safety information for Fmoc-N-amido-PEG24-acid
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for Fmoc-N-amido-PEG24-acid
| InChIKey | NFOMZHGRFWXDGH-UHFFFAOYSA-N |
| SMILES | C(OCC1C2=C(C=CC=C2)C2=C1C=CC=C2)(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O |
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